The purine nucleoside phosphorylase inhibitor forodesine (BCX-1777) is a potent cytotoxic agent and has synergistic activity with bendamustine in chronic lymphocytic leukemia (CLL) irrespective of ZAP-70 levels and p53 status.

被引：2

作者：

Alonso, Roberto ^{[1
,2
]}

Villamor, Neus ^{[1
,2
]}

Upshaw, Ramanda

Bantia, Shanta

Mehrling, Thomas ^{[3
]}

Campo, Elias ^{[1
,2
]}

Montserrat, Emili ^{[4
]}

Colomer, Dolors ^{[1
,2
]}

机构：

[1] Hosp Clin Barcelona, IDIBAPS, Dept Pathol, Hematopathol Unit, Barcelona, Spain

[2] BioCyst Pharmaceut, Birmingham, AL USA

[3] Mundipharma Int Ltd, Cambridge, England

[4] Hosp Clin Barcelona, Dept Hematol, IDIBAPS, Barcelona, Spain

来源：

关键词：

D O I：

10.1182/blood.V110.11.3122.3122

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

3122

引用

页码：918A / 919A

页数：2