Ecological and Evolutionary Benefits of Temperate Phage: What Does or Doesn't Kill You Makes You Stronger

被引：143

作者：

Harrison, Ellie ^{[1
]}

Brockhurst, Michael A. ^{[2
]}

机构：

[1] Univ Sheffield, Dept Anim & Plant Sci, Arthur Willis Environm Ctr, Sheffield, S Yorkshire, England

[2] Univ Sheffield, Dept Anim & Plant Sci, Alfred Denny Bldg, Sheffield, S Yorkshire, England

来源：

BIOESSAYS | 2017年 / 39卷 / 12期

基金：

欧洲研究理事会;

关键词：

experimental evolution; horizontal gene transfer; lysogenic conversion; microbial ecology; prophage; temperate phage; transduction; MEDIATED GENE-TRANSFER; SINGLE-CELL LEVEL; PSEUDOMONAS-AERUGINOSA; PROPHAGE INDUCTION; ESCHERICHIA-COLI; STAPHYLOCOCCUS-AUREUS; BACTERIAL PATHOGENS; BACTERIOPHAGE; HOST; GENOME;

D O I：

10.1002/bies.201700112

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Infection by a temperate phage can lead to death of the bacterial cell, but sometimes these phages integrate into the bacterial chromosome, offering the potential for a more long-lasting relationship to be established. Here we define three major ecological and evolutionary benefits of temperate phage for bacteria: as agents of horizontal gene transfer (HGT), as sources of genetic variation for evolutionary innovation, and as weapons of bacterial competition. We suggest that a coevolutionary perspective is required to understand the roles of temperate phages in bacterial populations.

引用

页数：6