Medullary thyroid carcinoma: The third most common thyroid cancer reviewed

被引:31
作者
Stamatakos, Michael [1 ]
Paraskeva, Panoraia [2 ]
Stefanaki, Charikleia [1 ]
Katsaronis, Paraskevas [2 ]
Lazaris, Andreas [3 ]
Safioleas, Konstantinos [1 ]
Kontzoglou, Konstantinos [2 ]
机构
[1] Univ Athens, Sch Med, Attikon Hosp, Dept Surg 4, GR-11527 Athens, Greece
[2] Univ Athens, Sch Med, Laiko Hosp, Dept Propaedeut Surg 2, GR-11527 Athens, Greece
[3] Univ Athens, Sch Med, Dept Pathol 1, GR-11527 Athens, Greece
关键词
thyroid gland; medullary thyroid carcinoma; calcitonin; thyroidectomy; FOLLOW-UP; MANAGEMENT; CALCITONIN; DIAGNOSIS; NEOPLASIA; SURVIVAL;
D O I
10.3892/ol.2010.223
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Medullary thyroid cancer is a type of thyroid cancer of neuroendocrine origin. It occurs in hereditary and sporadic forms, and its aggressive behavior is associated with the clinical presentation and type of RET mutation. Total thyroidectomy remains the ideal choice of treatment. Early diagnosis and treatment are the fundamental for a 100% cure rate. In this study, we present our experience of 3 cases, along with a complete review of the literature derived from a Pubmed Database search.
引用
收藏
页码:49 / 53
页数:5
相关论文
共 33 条
[1]   Medullary thyroid cancinoma - update and present management controversies [J].
Al-Rawi, Mahir ;
Wheeler, Malcolm H. .
ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 2006, 88 (05) :433-438
[2]  
[Anonymous], Cancer Facts & Figures
[3]   Medullary thyroid cancer: therapeutic targets and molecular markers [J].
Ball, Douglas W. .
CURRENT OPINION IN ONCOLOGY, 2007, 19 (01) :18-23
[4]  
Bardin CW, 1997, CURRENT THERAPY ENDO, P127
[5]  
Bergholm U, 1997, CANCER-AM CANCER SOC, V79, P132, DOI 10.1002/(SICI)1097-0142(19970101)79:1<132::AID-CNCR19>3.0.CO
[6]  
2-5
[7]   A population-based analysis of survival factors in differentiated and medullary thyroid carcinoma [J].
Bhattacharyya, N .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2003, 128 (01) :115-123
[8]  
Boikos SA, 2008, HISTOL HISTOPATHOL, V23, P109, DOI 10.14670/HH-23.109
[9]   Prognostic variables and calcitonin in medullary thyroid cancer [J].
Clark, JR ;
Fridman, TR ;
Odell, MJ ;
Brierley, J ;
Walfish, PG ;
Freeman, JL .
LARYNGOSCOPE, 2005, 115 (08) :1445-1450
[10]   Inhibition. of medullary thyroid carcinoma cell proliferation and RET phosphorylation by tyrosine kinase inhibitors [J].
Cohen, MS ;
Hussain, HB ;
Moley, JF .
SURGERY, 2002, 132 (06) :960-966