The pre-requisite of a second-generation glioma PET biomarker

被引:9
作者
Borbely, Katalin [1 ]
Wintermark, Max [2 ]
Martos, Janos [3 ]
Fedorcsak, Imre [4 ]
Bognar, Laszlo [5 ]
Kasler, Miklos
机构
[1] Natl Inst Oncol, PET CT Amb, H-1122 Budapest, Hungary
[2] Univ Virginia, Dept Radiol, Neuroradiol Div, Charlottesville, VA USA
[3] Natl Inst Neurosurg, Dept Neuroradiol, H-1145 Budapest, Hungary
[4] Natl Inst Neurosurg, Dept Neurosurg, H-1145 Budapest, Hungary
[5] Univ Debrecen, Fac Med, Dept Neurosurg, H-4032 Debrecen, Hungary
关键词
Glioma; PET; Biomarker; POSITRON-EMISSION-TOMOGRAPHY; GROWTH-FACTOR RECEPTOR; HYPOXIC CELL FRACTION; BRAIN-TUMORS; CEREBRAL GLIOMAS; C-11-ACETATE PET; RADIOLABELED FLUOROMISONIDAZOLE; GLIOBLASTOMA-MULTIFORME; F-18; FLUORODEOXYGLUCOSE; DIFFERENTIATING TUMOR;
D O I
10.1016/j.jns.2010.07.024
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Since the introduction of FDG into the field of molecular imaging with positron emission tomography (PET) more than three decades ago, FDG has been the tracer of choice for oncology PET imaging. Despite the relative disadvantages of FDG and the relative benefits of its challengers. FDG remains the most commonly used glioma tracer nowadays. The present article surveys the expectations of the field and gives a concise summary of recent developments; including the issues pertaining to the continued search for an optimal second-generation PET biomarker for glioma. Mini-abstract: The present article gives a concise summary of recent developments; including the issues pertaining to the continued search for an optimal PET biomarker for glioma. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:11 / 16
页数:6
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