Healing status of burn wound healing: ATR-FTIR study

被引：0

作者：

Castro, Pedro ^{[1
]}

Zorn, Telma ^{[2
]}

Zezell, Denise ^{[1
]}

机构：

[1] Nucl & Energy Res Inst, Ctr Lasers & Applicat CLA, IPEN CNEN SP, Sao Paulo, Brazil

[2] Univ Sao Paulo, Cell Biol & Dev Biol ICB, Sao Paulo, Brazil

来源：

2021 SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE (SBFOTON IOPC) | 2021年

基金：

巴西圣保罗研究基金会;

关键词：

ATR-FTIR; burned skin; wound healing;

D O I：

10.1109/SBFOTONIOPC50774.2021.9461956

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

The purpose of this study is to use infrared spectroscopy (FTIR) for monitoring biological changes in burned skin. Wistar rats dorsum samples were compared to healthy group samples at 7, 14, 21 days after burn. Proteins changes of burn wounds were monitored by area under the curve (AUC) of bands at 1630 cm(-1), 1543 cm(-1) and 1743 cm(-1). Kruskal Wallis normality tests, unpaired t test with Welch's correction were used to evaluate the differences between AUC. These bands suggest association between collagen activity during wound healing stages. Our result indicates progressive recovery of 7,14 and 21 days tissues when compared with the healthy group.

引用

页数：3

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