Hydroboration-azide alkylation as efficient tandem reactions for the synthesis of chiral non racemic substituted pyrrolidines

被引：17

作者：

Salmon, A ^{[1
]}

Carboni, B ^{[1
]}

机构：

[1] Univ Rennes 1, CNRS, UMR 6510, F-35042 Rennes, France

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 1998年 / 567卷 / 1-2期

关键词：

pyrrolidine; azide; organoborane; tandem reactions; non-racemic;

D O I：

10.1016/S0022-328X(98)00665-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The synthesis of chiral non racemic substituted pyrrolidines from homoallylic alcohols is presented. These precursors are readily converted via the azides to the corresponding pyrrolidines using hydroboration-cycloalkylation tandem reactions as key steps. (C) 1998 Elsevier Science S.A. All rights reserved.

引用

页码：31 / 37

页数：7

共 58 条

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