Chemical Composition and Antioxidant and Antimicrobial Activities of Wormwood (Artemisia absinthium L.) Essential Oils and Phenolics

被引：91

作者：

Msaada, Kamel ^{[1
,2
]}

Salem, Nidhal ^{[1
]}

Bachrouch, Olfa ^{[1
]}

Bousselmi, Slim ^{[1
]}

Tammar, Sonia ^{[1
]}

Alfaify, Abdulkhaleg ^{[2
]}

Al Sane, Khaldoun ^{[2
]}

Ben Ammar, Wided ^{[3
]}

Azeiz, Sana ^{[1
]}

Brahim, Adel Haj ^{[1
]}

Hammami, Majdi ^{[1
]}

Selmi, Sawsen ^{[1
]}

Limam, Ferid ^{[1
]}

Marzouk, Brahim ^{[1
]}

机构：

[1] Biotechnol Ctr Borj Cedria Technopol, Lab Bioact Subst, Hammam Lif 2050, Tunisia

[2] King Khalid Univ, Coll Sci, Dept Biol, Abha 61413, Saudi Arabia

[3] Univ Tunis, Unit Res Nitrogenized Nutr & Metab & Stress Prot, Dept Biol, Fac Sci, Tunis 2092, Tunisia

来源：

JOURNAL OF CHEMISTRY | 2015年 / 2015卷

关键词：

RADICAL SCAVENGING ACTIVITY; CALLUS-CULTURES; FLAVONOIDS; EXTRACTS; CONSTITUENTS; ANTIFUNGAL; SANTONICUM; COLEOPTERA; ASTERACEAE; PARTS;

D O I：

10.1155/2015/804658

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The aim of this study was to determine the chemical variability of worm wood extracts as affected by the growing region. Antioxidant and antimicrobial activities were also investigated. The essential oil composition variability of A. absinthium L. aerial parts collected from four different Tunisian regions was assessed by gas chromatography (GC/FID) and by gas chromatography mass spectrometry (GC/MS). In addition, total polyphenols, flavonoids, and condensed tannins as well as antioxidant, antibacterial, and antifungal activities of methanolic extract and essential oils were undertaken. Chromatographic analysis of worm wood essential oils showed the predominance of monoterpene hydrocarbons represented mainly by chamazulene. RP-HPLC analysis of wormwood methanolic extract revealed the predominance of phenolic acids. Antiradical activity was region-dependant and the methanolic extract of Bou Salem region has the strongest activity (CI50 = 9.38 +/- 0.82 mu g/mL). Concerning the reducing power, the methanolic extract of Bou Salem, Jerissa, and Boukornine regions was more active than the positive control. Obtained results of antimicrobial activities showed that wormwood essential oil is endowed with important antibacterial activity which was strongly related to the organoleptic quality of oil which appeared strongly region-dependant. A. absinthium L. EOs investigated are quite interesting from a pharmaceutical standpoint because of their biological activities.

引用

页数：12

共 58 条

[21]

Irshad S., 2011, International Research Journal of Pharmaceuticals, V1, P9

[22] Antioxidant activity of processed table beets (Beta vulgaris var, conditiva) and green beans (Phaseolus vulgaris L.) [J].

Jiratanan, T ;

Liu, RH .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (09) :2659-2670

[23] Composition and antimicrobial activity of the essential oil of Artemisia absinthium from Croatia and France [J].

Juteau, F ;

Jerkovic, I ;

Masotti, V ;

Milos, M ;

Mastelic, J ;

Bessière, JM ;

Viano, J .

PLANTA MEDICA, 2003, 69 (02) :158-161

[24]

KEDZIA B, 1991, Herba Polonica, V37, P29

[25] Toxicity of essential oils isolated from three Artemisia species and some of their major components to granary weevil, Sitophilus granarius (L.) (Coleoptera: Curculionidae) [J].

Kordali, S ;

Aslan, I ;

Çalmasur, O ;

Cakir, A .

INDUSTRIAL CROPS AND PRODUCTS, 2006, 23 (02) :162-170

[26] Determination of the chemical composition and antioxidant activity of the essential oil of Artemisia dracunculus and of the antifungal and antibacterial activities of Turkish Artemisia absinthium, A-dracunculus, Artemisia santonicum, and Artemisia spicigera essential oils [J].

Kordali, S ;

Kotan, R ;

Mavi, A ;

Cakir, A ;

Ala, A ;

Yildirim, A .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2005, 53 (24) :9452-9458

[27] Screening of chemical composition and antifungal and antioxidant activities of the essential oils from three Turkish Artemisia species [J].

Kordali, S ;

Cakir, A ;

Mavi, A ;

Kilic, H ;

Yildirim, A .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2005, 53 (05) :1408-1416

[28] Essential oils from Asteraceae as potential biocontrol tools for tomato pests and diseases [J].

Laura Umpierrez, Maria ;

Eugenia Lagreca, Maria ;

Cabrera, Raimundo ;

Grille, Gabriela ;

Rossini, Carmen .

PHYTOCHEMISTRY REVIEWS, 2012, 11 (04) :339-350

[29]

LAWRENCE B M, 1992, Perfumer and Flavorist, V17, P39

[30] Tetramethoxy hydroxyflavone p7F downregulates inflammatory mediators via the inhibition of nuclear factor κB [J].

Lee, HG ;

Kim, H ;

Oh, WK ;

Yu, KA ;

Choe, YK ;

Ahn, JS ;

Kim, DS ;

Kim, SH ;

Dinarello, CA ;

Kim, K ;

Yoon, DY .

SIGNAL TRANSDUCTION PATHWAYS, CHROMATIN STRUCTURE, AND GENE EXPRESSION MECHANISMS AS THERAPEUTIC TARGETS, 2004, 1030 :555-568

← 1 2 3 4 5 6 →