Genetic Variants of HIV Type 1 in Men Who Have Sex with Men in Russia

被引：0

作者：

Kazennova, Elena ^{[1
]}

Laga, Vita ^{[1
]}

Gromov, Konstantin ^{[1
]}

Lebedeva, Nataliya ^{[2
]}

Zhukova, Eugenia ^{[2
]}

Pronin, Alexander ^{[2
]}

Grezina, Liliya ^{[3
]}

Dement'eva, Nataliya ^{[4
]}

Shemshura, Andrey ^{[5
]}

Bobkova, Marina ^{[1
]}

机构：

[1] Ivanovsky Inst Virol, Gamaleya Ctr Epidemiol & Microbiol, 16 Gamaleya St, Moscow 123098, Russia

[2] Moscow Reg AIDS Ctr, Moscow, Russia

[3] Yamalo Nenets Reg AIDS Ctr, Noyabrsk, Russia

[4] St Petersburg Municipal AIDS Ctr, St Petersburg, Russia

[5] Southern Fed AIDS Ctr, Rostov Na Donu, Russia

来源：

AIDS RESEARCH AND HUMAN RETROVIRUSES | 2017年 / 33卷 / 10期

基金：

俄罗斯科学基金会;

关键词：

HIV; MSM; subtypes; Russia; EPIDEMIOLOGY; SUBTYPE;

D O I：

10.1089/aid.2017.0078

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The men who have sex with men (MSM) population infected with HIV is poorly studied in Russia because of stigma and discrimination. In the first years of the HIV epidemic, the only HIV genetic variant that circulated among MSM was subtype B, usually acquired abroad. Meanwhile, the massive epidemic of HIV in Russia was caused by a highly homogenic subtype A variant, A(FSU) (A6), and spread mainly among drug users. In this study, 155 HIV pol sequences from MSM collected during the 2006-2016 period were analyzed. Phylogenetic analysis found that 19.4% of the viral sequences from MSM clustered with HIV genetic variants A6 and B-FSU, which were previously identified only among drug users and their heterosexual partners. These data show that the MSM population in Russia is gradually becoming less isolated from the general epidemic process. Urgent measures should be taken to prevent the spread of HIV among the MSM population.

引用

页码：1061 / 1064

页数：4

共 13 条

[1] Predictors of HIV risk behavior among Russian men who have sex with men: an emerging epidemic [J].

Amirkhanian, YA ;

Kelly, JA ;

Kukharsky, AA ;

Borodkina, OI ;

Granskaya, JV ;

Dyatlov, RV ;

McAuliffe, TL ;

Kozlov, AP .

AIDS, 2001, 15 (03) :407-412

[2]

[Anonymous], 2016, Global AIDS Update 2016

[3] A sudden epidemic of HIV type 1 among injecting drug users in the former Soviet Union:: Identification of subtype A, subtype B, and novel gagA/envB recombinants [J].

Bobkov, A ;

Kazennova, E ;

Selimova, L ;

Bobkova, M ;

Khanina, T ;

Ladnaya, N ;

Kravchenko, A ;

Pokrovsky, V ;

Cheingsong-Popov, R ;

Weber, J .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1998, 14 (08) :669-676

[4]

Bobkova M, 2013, AIDS REV, V15, P204

[5] Primate immunodeficiency virus classification and nomenclature: Review [J].

Foley, Brian T. ;

Leitner, Thomas ;

Paraskevis, Dimitrios ;

Peeters, Martine .

INFECTION GENETICS AND EVOLUTION, 2016, 46 :150-158

[6] HIV risk characteristics and prevention needs in a community sample of bisexual men in St. Petersburg, Russia [J].

Kelly, JA ;

Amirkhanian, YA ;

McAuliffe, TL ;

Granskaya, JV ;

Borodkina, OI ;

Dyatlov, RV ;

Kukharsky, A ;

Kozlov, AP .

AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV, 2002, 14 (01) :63-76

[7] Epidemiological Networks and Drug Resistance of HIV Type 1 in Krasnoyarsk Region, Russia [J].

Rumyantseva, Olga A. ;

Olkhovskiy, Igor A. ;

Malysheva, Marina A. ;

Ruzaeva, Ludmila A. ;

Vasiliev, Alexander V. ;

Kazennova, Elena V. ;

Bobkova, Marina R. ;

Lukashov, Vladimir V. .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2009, 25 (09) :931-936

[8]

Russian Federal AIDS Centre, 2015, STAT B HIV INFECT RU

[9] Molecular epidemiology of HIV type 1 in Ukraine: Birthplace of an epidemic [J].

Saad, Magdi Darwish ;

Shcherbinskaya, Alla M. ;

Nadai, Yuka ;

Kruglov, Yuri V. ;

Antonenko, Svietlana V. ;

Lyullchuk, Mariya G. ;

Kravchenko, Olga N. ;

Earhart, Kenneth C. ;

Sanchez, Jose L. ;

Birx, Debora L. ;

Kirkland Carr, Jean .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2006, 22 (08) :709-714

[10] HIV epidemiology in the northwestern Federal District of Russia: Dominance of HIV type 1 subtype A [J].

Smolskaya, Tatiana ;

Liitsola, Kirsi ;

Zetterberg, Veera ;

Golovanova, Elena ;

Kevlova, Natalia ;

Konovalova, Nadezda ;

Sevastianova, Ksenia ;

Brummer-Korvenkontio, Henrikki ;

Salminen, Mika .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2006, 22 (11) :1074-1080

← 1 2 →