Four additional meroterpenes produced by Penicillium sp found in association with Melia azedarach.: Possible Biosynthetic intermediates to austin

被引：35

作者：

Fill, Taicia Pacheco

Pereira, Grace Kelli

dos Santos, Regina M. Geris

Rodrigues-Fo, Edson ^{[1
]}

机构：

[1] Univ Fed Sao Carlos, Dept Quim, BR-13565905 Sao Carlos, SP, Brazil

[2] Univ Fed Bahia, Inst Quim, Dept Quim Organ, BR-40170270 Salvador, Brazil

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2007年 / 62卷 / 08期

基金：

巴西圣保罗研究基金会;

关键词：

melia azedarach; penicillium; endophytic fungi; meroterpenes; meroterpenoids;

D O I：

10.1515/znb-2007-0806

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Four additional meroterpenes were isolated and identified from rice cultures of Penicillium sp, a fungus obtained from the root bark of Melia azedarach. These new compounds were named preaustinoid B2 (1), preaustinoid A3 (2), austinolide (3), and isoaustinone (4) in analogy with the formerly described compounds. The structures were identified by extensive spectroscopic studies, including 1 D and 2 D NMR spectroscopy and HRMS. Compounds 1 - 4 are probably biosynthetic intermediates to Austin.

引用

页码：1035 / 1044

页数：10

共 10 条

[1] STUDIES ON THE BIOSYNTHESIS OF THE MYCOTOXIN AUSTIN, A MEROTERPENOID METABOLITE OF ASPERGILLUS-USTUS [J].