Targeting Apoptosis Inhibition to Activate Antitumor Immunity

被引：8

作者：

Kesavardhana, Sannula ^{[1
]}

Kanneganti, Thirumala-Devi ^{[1
]}

机构：

[1] St Jude Childrens Res Hosp, Dept Immunol, 332 N Lauderdale St, Memphis, TN 38105 USA

来源：

TRENDS IN IMMUNOLOGY | 2019年 / 40卷 / 12期

基金：

美国国家卫生研究院;

关键词：

CELL-DEATH;

D O I：

10.1016/j.it.2019.11.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A recent study by Rodriguez-Ruiz et al. suggests that inhibition of apoptotic caspases can augment radiation-induced antitumor immunity, independent of type I IFN. Their findings also highlight caspase-independent cytotoxicity in radiation therapy- induced antitumor immunity, pro-posing SLC7A2 as a new putative prognostic marker for breast cancer.

引用

页码：1073 / 1075

页数：4

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