Regulation of expression of the fibronectin-binding protein BBK32 in Borrelia burgdorferi

被引:23
作者
He, Ming [1 ]
Boardman, Bethany K. [1 ]
Yan, Dalai [1 ]
Yang, X. Frank [1 ]
机构
[1] Indiana Univ, Sch Med, Dept Microbiol & Immunol, Indianapolis, IN 46202 USA
关键词
D O I
10.1128/JB.01199-07
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The BBK32 protein binds to host extracellular ligand fibronectin and contributes to the pathogenesis of Borrelia burgdorferi. Here we showed that expression of the BBK32 gene is influenced by multiple environmental factors and that its regulation is governed by the response regulator Rrp2 and RpoN-RpoS (sigma(54)-sigma(S)) sigma cascade in B. burgdorferi.
引用
收藏
页码:8377 / 8380
页数:4
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