Does the human ventromedial prefrontal cortex support fear learning, fear extinction or both? A commentary on subregional contributions

被引：91

作者：

Battaglia, Simone ^{[1
]}

Harrison, Ben J. ^{[2
]}

Fullana, Miquel A. ^{[3
,4
]}

机构：

[1] Univ Bologna, Dept Psychol, Ctr Studies & Res Cognit Neurosci, Bologna, Italy

[2] Univ Melbourne & Melbourne Hlth, Dept Psychiat, Melbourne Neuropsychiat Ctr, Melbourne, Vic, Australia

[3] Hosp Clin Barcelona, Inst Neurosci, Adult Psychiat & Psychol Dept, Barcelona, Spain

[4] CIBERSAM, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Barcelona, Spain

来源：

MOLECULAR PSYCHIATRY | 2022年 / 27卷 / 02期

关键词：

D O I：

10.1038/s41380-021-01326-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Current models of human fear learning processes emphasize a primary contribution of the ventromedial prefrontal cortex (vmPFC) to fear inhibition (i.e., fear extinction). Here, we discuss crucial findings from recent brain imaging studies that highlight the role of vmPFC and its subregions in how fear is acquired (i.e., fear conditioning).

引用

页码：784 / 786

页数：3

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