Rhodium Catalyzed C2-Selective Cyanation of Indoles and Pyrroles

被引：63

作者：

Chaitanya, Manthena ^{[1
]}

Anbarasan, Pazhamalai ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Madras 600036, Tamil Nadu, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 80卷 / 07期

关键词：

H BOND CYANATION; C-H; MEDIATED CYANATION; ARYL HALIDES; CONVERSION; CYANIDE; TRANSFORMATION; HETEROARENES; DERIVATIVES; AROMATICS;

D O I：

10.1021/acs.joc.5b00142

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and general rhodium(III) catalyzed C2-selective cyanation of indoles and pyrroles was accomplished employing easily accessible and environmentally friendly cyanating reagent, NCTS. This methodology tolerates various functional groups, uses readily removable directing groups and allows the synthesis of various 2-cyanoindoles and pyrroles in good to excellent yield.

引用

页码：3695 / 3700

页数：6

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