Adult Obstructive Sleep Apnea/Hypopnea Syndrome: Definitions, Risk Factors, and Pathogenesis

被引：87
作者：
Yaggi, H. Klar [1 ,2 ]
Strohl, Kingman P. [3 ]
机构：
[1] Yale Univ, Sch Med, Div Pulm & Crit Care Med, New Haven, CT 06520 USA
[2] VA CT Hlth Care Syst, W Haven VA Med Ctr Sleep Lab, Clin Epidemiol Res Ctr, West Haven, CT 06516 USA
[3] Ctr Sleep Educ & Res, Case Western Reserve Sch Med, Dept Med, Cleveland, OH 44106 USA
来源：
CLINICS IN CHEST MEDICINE | 2010年 / 31卷 / 02期
关键词：
Epidemiology; Obstructive sleep apnea syndrome; Pathogenesis; Risk factors; BODY POSITIVE-PRESSURE; UPPER AIRWAY; GENDER-DIFFERENCES; HEALTHY-SUBJECTS; AFRICAN-AMERICANS; HEART HEALTH; APNEA; POPULATION; COMMUNITY; WOMEN;
D O I：
10.1016/j.ccm.2010.02.011
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
The objectives of this article are to (1) understand how respiratory event definitions and syndrome threshold values affect prevalence estimates of obstructive sleep apnea in adults, (2) recognize important risk factors for obstructive sleep apnea in adults, and (3) understand current theories of the underlying mechanisms for airway obstruction during sleep.
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页码：179 / +
页数：9
相关论文
共 52 条
[1]   Genetic polymorphisms and disease [J].
Altshuler, D ;
Kruglyak, L ;
Lander, E .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (22) :1626-1626
[2]   SLEEP-DISORDERED BREATHING IN AFRICAN-AMERICAN ELDERLY [J].
ANCOLIISRAEL, S ;
KLAUBER, MR ;
STEPNOWSKY, C ;
ESTLINE, E ;
CHINN, A ;
FELL, R .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1995, 152 (06) :1946-1949
[3]   SLEEP-DISORDERED BREATHING IN COMMUNITY-DWELLING ELDERLY [J].
ANCOLIISRAEL, S ;
KRIPKE, DF ;
KLAUBER, MR ;
MASON, WJ ;
FELL, R ;
KAPLAN, O .
SLEEP, 1991, 14 (06) :486-495
[4]   Effects of age on sleep apnea in men I. Prevalence and severity [J].
Bixler, EO ;
Vgontzas, AN ;
Ten Have, T ;
Tyson, K ;
Kales, A .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998, 157 (01) :144-148
[5]   Prevalence of sleep-disordered breathing in women - Effects of gender [J].
Bixler, EO ;
Vgontzas, AN ;
Lin, HM ;
Ten Have, T ;
Rein, J ;
Vela-Bueno, A ;
Kales, A .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (03) :608-613
[6]   The relationship between craniofacial morphology and obstructive sleep apnea in whites and in African-Americans [J].
Cakirer, B ;
Hans, MG ;
Graham, G ;
Aylor, J ;
Tishler, PV ;
Redline, S .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (04) :947-950
[7]   Genetic and environmental influences in sleep-disordered breathing in older male twins [J].
Carmelli, D ;
Colrain, IM ;
Swan, GE ;
Bliwise, DL .
SLEEP, 2004, 27 (05) :917-922
[8]   A genetic analysis of the Epworth Sleepiness Scale in 1560 World War II male veteran twins in the NAS-NRC Twin Registry [J].
Carmelli, D ;
Bliwise, DL ;
Swan, GE ;
Reed, T .
JOURNAL OF SLEEP RESEARCH, 2001, 10 (01) :53-58
[9]   Fluid shift by lower body positive pressure increases pharyngeal resistance in healthy subjects [J].
Chiu, Kuo-Liang ;
Ryan, Clodagh M. ;
Shiota, Satomi ;
Ruttanaumpawan, Pimon ;
Arzt, Michael ;
Haight, James S. ;
Chan, Christopher T. ;
Floras, John S. ;
Bradley, T. Douglas .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2006, 174 (12) :1378-1383
[10]   Gender differences in sleep and sleep-disordered breathing [J].
Collop, NA ;
Adkins, D ;
Phillips, BA .
CLINICS IN CHEST MEDICINE, 2004, 25 (02) :257-+
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