Highly efficient and chemoselective trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS) catalyzed by reusable electron-deficient [TiIV(salophen)(OTf)2]

被引：15

作者：

Yadegari, Maryam ^{[2
]}

Moghadam, Majid ^{[1
]}

Tangestaninejad, Shahram ^{[1
]}

Mirkhani, Valiollah ^{[1
]}

Mohammadpoor-Baltork, Iraj ^{[1
]}

机构：

[1] Univ Isfahan, Dept Chem, Catalysis Div, Esfahan 817467344, Iran

[2] Islamic Azad Univ, Dept Chem, Sci & Res Branch, Tehran, Iran

来源：

POLYHEDRON | 2012年 / 31卷 / 01期

关键词：

Titanium Schiff base; HMDS; Alcohol; Phenol; TMS-ether; HIGH-VALENT METALLOPORPHYRIN; ALLYL VINYL ETHERS; HYDROXYL-GROUPS; ENANTIOSELECTIVE TRIMETHYLSILYLCYANATION; 1,1,1,3,3,3-HEXAMETHYLDISILAZANE HMDS; TIN(IV) PORPHYRIN; O-SILYLATION; ACID; PROTECTION; EPOXIDES;

D O I：

10.1016/j.poly.2011.09.023

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

In the present work, highly efficient trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS) catalyzed by high-valent [Ti-IV(salophen)(OTf)(2)] is reported. Under these conditions, primary, secondary and tertiary alcohols as well as phenols were silylated in short reaction times and high yields. It is noteworthy that this method can be used for chemoselective silylation of primary alcohols in the presence of secondary and tertiary alcohols and phenols. The catalyst was reused several times without loss of its catalytic activity. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：332 / 338

页数：7

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