High Prevalence of blaNDM-1 Carbapenemase-Encoding Gene and 16S rRNA armA Methyltransferase Gene among Acinetobacter baumannii Clinical Isolates in Egypt

被引：42

作者：

El-Sayed-Ahmed, Mohamed Abd El-Gawad ^{[1
,2
]}

Amin, Magdy Ali ^{[3
]}

Tawakol, Wael Mustafa ^{[2
]}

Loucif, Lotfi ^{[1
]}

Bakour, Sofiane ^{[1
]}

Rolain, Jean-Marc ^{[1
]}

机构：

[1] Aix Marseille Univ, Fac Med & Pharm, IHU Mediterranee Infect,Unite Rech Malad Infect &, INSERM 1095,IRD 198,CNRS 7278,UM63, Marseille, France

[2] Misr Univ Sci & Technol, Fac Pharm, Dept Microbiol & Immunol, Cairo, Egypt

[3] Cairo Univ, Fac Pharm, Dept Microbiol & Immunol, Cairo, Egypt

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2015年 / 59卷 / 06期

关键词：

METALLO-BETA-LACTAMASE; PSEUDOMONAS-SPP; EMERGENCE; SPREAD;

D O I：

10.1128/AAC.04412-14

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The main objective of this study was to decipher the molecular mechanism of resistance to carbapenems and aminoglycosides in a large series of 150 Acinetobacter baumannii clinical isolates collected from July 2012 to September 2013 in Egypt. We report for the first time the emergence of blaNDM-1 and the cooccurrence of 16S rRNA methylase armA with bla(NDM-1) and bla(OXA-23) in Egyptian hospitals. Multilocus sequence typing identified 27 distinct sequence types, 11 of which were novel.

引用

页码：3602 / 3605

页数：4

共 23 条

[1]

Abd El Gawad M, 2014, ABSTR 24TH EUR CONGR

[2]

Al-Agamy MH, 2014, INT J INFECT DIS, V22, P49, DOI [10.10, 10.1016/j.ijid.2013.12.004]

[3] Diversity in Acinetobacter baumannii isolates from paediatric cancer patients in Egypt [J].