High Prevalence of blaNDM-1 Carbapenemase-Encoding Gene and 16S rRNA armA Methyltransferase Gene among Acinetobacter baumannii Clinical Isolates in Egypt

被引：39
作者：
El-Sayed-Ahmed, Mohamed Abd El-Gawad [1 ,2 ]
Amin, Magdy Ali [3 ]
Tawakol, Wael Mustafa [2 ]
Loucif, Lotfi [1 ]
Bakour, Sofiane [1 ]
Rolain, Jean-Marc [1 ]
机构：
[1] Aix Marseille Univ, Fac Med & Pharm, IHU Mediterranee Infect,Unite Rech Malad Infect &, INSERM 1095,IRD 198,CNRS 7278,UM63, Marseille, France
[2] Misr Univ Sci & Technol, Fac Pharm, Dept Microbiol & Immunol, Cairo, Egypt
[3] Cairo Univ, Fac Pharm, Dept Microbiol & Immunol, Cairo, Egypt
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2015年 / 59卷 / 06期
关键词：
METALLO-BETA-LACTAMASE; PSEUDOMONAS-SPP; EMERGENCE; SPREAD;
D O I：
10.1128/AAC.04412-14
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The main objective of this study was to decipher the molecular mechanism of resistance to carbapenems and aminoglycosides in a large series of 150 Acinetobacter baumannii clinical isolates collected from July 2012 to September 2013 in Egypt. We report for the first time the emergence of blaNDM-1 and the cooccurrence of 16S rRNA methylase armA with bla(NDM-1) and bla(OXA-23) in Egyptian hospitals. Multilocus sequence typing identified 27 distinct sequence types, 11 of which were novel.
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收藏
页码：3602 / 3605
页数：4
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