Animal models used in identifying gender-related differences

被引:20
作者
Curry, BB [1 ]
机构
[1] Charles River Labs Discovery & Dev Serv, Lab Anim Resources, Worcester, MA 01608 USA
关键词
animal models; gender difference; mice; monkey; rabbit; rat;
D O I
10.1080/109158101317097737
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
There is general agreement in the scientific community on the need to identify appropriate animal models that can be used to screen for gender-based differences. At the same time, there is a growing expectation for data from these models to mimic or be more predictive of the human experience. The species in this review will include nonhuman primates, rats, mice, rabbits, swine, hamsters, gerbils, quail, and fish. Although some of the models are unique, the gender-related differences, in most instances, may be correlated with man, due to the conservation of biological systems across species.
引用
收藏
页码:153 / 160
页数:8
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