Alkane-oxidizing metalloenzymes in the carbon cycle

被引：58

作者：

Austin, Rachel Narehood ^{[1
]}

Groves, John T. ^{[2
]}

机构：

[1] Bates Coll, Dept Chem, Lewiston, ME 04240 USA

[2] Princeton Univ, Dept Chem, Princeton, NJ 08544 USA

来源：

METALLOMICS | 2011年 / 3卷 / 08期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

CHAIN N-ALKANES; SUBSTRATE RADICAL INTERMEDIATE; ACINETOBACTER SP M-1; PARTICULATE METHANE MONOOXYGENASE; METHYLOCOCCUS-CAPSULATUS BATH; SULFATE-REDUCING BACTERIUM; H BOND ACTIVATION; GULF-OF-MEXICO; PSEUDOMONAS-OLEOVORANS; XYLENE MONOOXYGENASE;

D O I：

10.1039/c1mt00048a

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review examines the metalloenzymes that catalyze the oxidation of alkanes in the environment. The focus of the review is on what is known about the relative abundances of these metalloenzymes, their metal ion requirements, and their reaction mechanisms. The relative significance of these reactions in the global transformation of alkanes is discussed.

引用

收藏

页码：775 / 787

页数：13

相关论文

共 148 条

[1] Growth, natural relationships, cellular fatty acids and metabolic adaptation of sulfate-reducing bacteria that utilize long-chain alkanes under anoxic conditions [J].

Aeckersberg, F ;

Rainey, FA ;

Widdel, F .

ARCHIVES OF MICROBIOLOGY, 1998, 170 (05) :361-369

[2] Relationship between β-oxidation pathway and the hydrocarbon-degrading profile in actinomycetes bacteria [J].

Alvarez, HM .

INTERNATIONAL BIODETERIORATION & BIODEGRADATION, 2003, 52 (01) :35-42

[3]

ANTHONY C, 1983, CARBON SUBSTRATES BI, V21, P93

[4] Methane and related trace species on Mars: Origin, loss, implications for life, and habitability [J].

Atreya, Sushil K. ;

Mahaffy, Paul R. ;

Wong, Ah-San .

PLANETARY AND SPACE SCIENCE, 2007, 55 (03) :358-369

[5] Cage escape competes with geminate recombination during alkane hydroxylation by the diiron oxygenase AlkB [J].

Austin, Rachel N. ;

Luddy, Kate ;

Erickson, Karla ;

Pender-Cudlip, Marilla ;

Bertrand, Erin ;

Deng, Dayi ;

Buzdygon, Ryan S. ;

van Beilen, Jan B. ;

Groves, John T. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (28) :5232-5234

[6] The diagnostic substrate bicyclohexane reveals a radical mechanism for bacterial cytochrome P450 in whole cells [J].

Austin, Rachel N. ;

Deng, Dayi ;

Jiang, Yongying ;

Luddy, Kate ;

van Beilen, Jan B. ;

de Montellano, Paul R. Ortiz ;

Groves, John T. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (48) :8192-8194

[7] The non-heme diiron alkane monooxygenase of Pseudomonas oleovorans (AlkB) hydroxylates via a substrate radical intermediate [J].

Austin, RN ;

Chang, HK ;

Zylstra, GJ ;

Groves, JT .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (47) :11747-11748

[8] Xylene monooxygenase, a membrane-spanning non-heme diiron enzyme that hydroxylates hydrocarbons via a substrate radical intermediate [J].

Austin, RN ;

Buzzi, K ;

Kim, E ;

Zylstra, GJ ;

Groves, JT .

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2003, 8 (07) :733-740

[9] Mechanistic studies on the hydroxylation of methane by methane monooxygenase [J].

Baik, MH ;

Newcomb, M ;

Friesner, RA ;

Lippard, SJ .

CHEMICAL REVIEWS, 2003, 103 (06) :2385-2419

[10] Oxidation of methane by a biological dicopper centre [J].

Balasubramanian, Ramakrishnan ;

Smith, Stephen M. ;

Rawat, Swati ;

Yatsunyk, Liliya A. ;

Stemmler, Timothy L. ;

Rosenzweig, Amy C. .

NATURE, 2010, 465 (7294) :115-U131

← 1 2 3 4 5 6 7 8 9 10 →