Cyclodextrins and emulsions

被引:78
|
作者
Duchêne, D [1 ]
Bochot, A [1 ]
Yu, SC [1 ]
Pépin, C [1 ]
Seiller, M [1 ]
机构
[1] Univ Paris Sud, UMR 8612, CNRS, Fac Pharm, F-92290 Chatenay Malabry, France
关键词
cyclodextrins; emulsions; multiple emulsions; fatty acids; glycerides;
D O I
10.1016/S0378-5173(03)00384-3
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
This paper synthesises the literature on interactions between cyclodextrins (CD) and fatty acids and glycerides, and explains how these interactions allow the use of cyclodextrins to stabilise emulsions. An example of formulation with cyclodextrins is given which discusses the preparation of simple o/w emulsions, the addition of a model active ingredient, and the preparation of multiple emulsions in the absence of preformed surface active agents. (C) 2003 Published by Elsevier B.V.
引用
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页码:85 / 90
页数:6
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