Cyclodextrins and emulsions

被引:78
作者
Duchêne, D [1 ]
Bochot, A [1 ]
Yu, SC [1 ]
Pépin, C [1 ]
Seiller, M [1 ]
机构
[1] Univ Paris Sud, UMR 8612, CNRS, Fac Pharm, F-92290 Chatenay Malabry, France
关键词
cyclodextrins; emulsions; multiple emulsions; fatty acids; glycerides;
D O I
10.1016/S0378-5173(03)00384-3
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
This paper synthesises the literature on interactions between cyclodextrins (CD) and fatty acids and glycerides, and explains how these interactions allow the use of cyclodextrins to stabilise emulsions. An example of formulation with cyclodextrins is given which discusses the preparation of simple o/w emulsions, the addition of a model active ingredient, and the preparation of multiple emulsions in the absence of preformed surface active agents. (C) 2003 Published by Elsevier B.V.
引用
收藏
页码:85 / 90
页数:6
相关论文
共 24 条
  • [1] DUCHENE D, 1999, ACTIFS ADDITIFS COSM, P57
  • [2] DUCHENE D, 1996, FORMES PHARM APPL LO, P480
  • [3] Duchene D., 1987, CYCLODEXTRINS THEIR, P299
  • [4] COMPLEXATION OF CARBOXYLIC-ACIDS AND ANIONS BY ALPHA-CYCLODEXTRINS AND BETA-CYCLODEXTRINS
    GELB, RI
    SCHWARTZ, LM
    [J]. JOURNAL OF INCLUSION PHENOMENA, 1989, 7 (04): : 465 - 476
  • [5] Grossiord J., 1998, MULTIPLE EMULSIONS S
  • [6] JAEGERLEZER N, 1997, J CONTROL RELEASE, V45, P1
  • [7] NUCLEAR-MAGNETIC-RESONANCE STUDIES OF CYCLODEXTRIN COMPLEXES OF LINOLEIC-ACID AND ARACHIDONIC-ACID
    JYOTHIRMAYI, N
    RAMADOSS, CS
    DIVAKAR, S
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1991, 39 (12) : 2123 - 2127
  • [8] Molecular dynamics simulation of cyclodextrin inclusion complexes in enzymatic lipid hydrolysis
    Kolossvary, GJ
    Kolossvary, I
    [J]. BIOTECHNOLOGY LETTERS, 1996, 18 (04) : 440 - 444
  • [9] INTERACTIONS BETWEEN BETA-CYCLODEXTRIN AND INSOLUBLE GLYCERIDE MONOMOLECULAR FILMS AT THE ARGON WATER INTERFACE - APPLICATION TO LIPASE KINETICS
    LAURENT, S
    IVANOVA, MG
    PIOCH, D
    GRAILLE, J
    VERGER, R
    [J]. CHEMISTRY AND PHYSICS OF LIPIDS, 1994, 70 (01) : 35 - 42
  • [10] LAURENT S, 1994, UNPUB CIRAD