Highly Enantioselective [4+2] Cycloaddition of Allenoates and 2-Olefinic Benzofuran-3-ones

被引：54

作者：

Wang, Feng ^{[1
]}

Luo, Chao ^{[1
]}

Shen, Ye-Ye ^{[1
]}

Wang, Ze-Dong ^{[1
]}

Li, Xin ^{[1
]}

Cheng, Jin-Pei ^{[1
]}

机构：

[1] Nankai Univ, State Key Lab Elementoorgan Chem, Collaborat Innovat Ctr Chem Sci & Engn, Dept Chem Tianjin, Tianjin 300071, Peoples R China

来源：

ORGANIC LETTERS | 2015年 / 17卷 / 02期

基金：

中国国家自然科学基金;

关键词：

MICHAEL ADDITION-REACTIONS; MORITA-BAYLIS-HILLMAN; 3-SUBSTITUTED BENZOFURAN-2(3H)-ONES; BROUSSONETIA PAPYRIFERA; NITROGEN-HETEROCYCLES; ASYMMETRIC-SYNTHESIS; PHOSPHINE CATALYSIS; CONCISE SYNTHESIS; FACILE SYNTHESIS; ALLENIC ESTERS;

D O I：

10.1021/ol503447z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly enantioselective [4 + 2] cycloaddition of allenoates with 2-olefinic benzofuran-3-ones catalyzed by (DHQD)(2)AQN, which allowed the synthesis of optically active dihydropyran-fused benzofurans, was developed.

引用

页码：338 / 341

页数：4

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