Iridium-Catalyzed Highly Enantioselective Hydrogenation of Exocyclic α,β-Unsaturated Carbonyl Compounds

被引：95

作者：

Tian, Fengtao ^{[1
]}

Yao, Dongmei ^{[1
]}

Liu, Yuanyuan ^{[1
]}

Xie, Fang ^{[1
]}

Zhang, Wanbin ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, Shanghai 200240, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2010年 / 352卷 / 11-12期

基金：

中国国家自然科学基金;

关键词：

asymmetric synthesis; cyclic carbonyl compounds; hydrogenation; iridium; oxazoline; OLD YELLOW ENZYME; ASYMMETRIC HYDROGENATION; OXAZOLINE LIGANDS; C=C BOND; COMPLEXES; OLEFINS; ALPHA; ALKYLATION; PD; PSEUDOEPHEDRINE;

D O I：

10.1002/adsc.201000185

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

By using the iridium complex of a phosphine-oxazoline ligand with an axis-unfixed biphenyl backbone, a highly enantioselective hydrogenation of the C=C bond of exocyclic alpha,beta-unsaturated carbonyl compounds to afford a-chiral cyclic ketones, lactones and lactams was developed.

引用

页码：1841 / 1845

页数：5

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