Iridium-Catalyzed Highly Enantioselective Hydrogenation of Exocyclic α,β-Unsaturated Carbonyl Compounds

被引：95
|
作者：
Tian, Fengtao [1 ]
Yao, Dongmei [1 ]
Liu, Yuanyuan [1 ]
Xie, Fang [1 ]
Zhang, Wanbin [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, Shanghai 200240, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2010年 / 352卷 / 11-12期
基金：
中国国家自然科学基金;
关键词：
asymmetric synthesis; cyclic carbonyl compounds; hydrogenation; iridium; oxazoline; OLD YELLOW ENZYME; ASYMMETRIC HYDROGENATION; OXAZOLINE LIGANDS; C=C BOND; COMPLEXES; OLEFINS; ALPHA; ALKYLATION; PD; PSEUDOEPHEDRINE;
D O I：
10.1002/adsc.201000185
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
By using the iridium complex of a phosphine-oxazoline ligand with an axis-unfixed biphenyl backbone, a highly enantioselective hydrogenation of the C=C bond of exocyclic alpha,beta-unsaturated carbonyl compounds to afford a-chiral cyclic ketones, lactones and lactams was developed.
引用
收藏
页码：1841 / 1845
页数：5
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