Public health relevance of drug-nutrition interactions

被引:27
作者
Peter, Szabolcs [1 ]
Navis, Gerjan [2 ]
de Borst, Martin H. [2 ]
von Schacky, Clemens [3 ,4 ]
van Orten-Luiten, Anne Claire B. [5 ,6 ]
Zhernakova, Alexandra [2 ]
Witkamp, Renger F. [5 ]
Janse, Andre [6 ]
Weber, Peter [1 ,7 ]
Bakker, Stephan J. L. [2 ]
Eggersdorfer, Manfred [1 ,2 ]
机构
[1] DSM Nutr Prod Ltd, Wurmisweg 576, CH-4303 Kaiseraugst, Switzerland
[2] Univ Groningen, Univ Med Ctr Groningen, Hanzepl 1, NL-9713 GZ Groningen, Netherlands
[3] Ludwig Maximilians Univ Munchen, Med Klin & Poliklin 1, Prevent Cardiol, Ziemssenstr 15, D-80336 Munich, Germany
[4] Omegametrix GmbH, Klopferspitz 19, D-82152 Martinsried, Germany
[5] Wageningen Univ, Div Human Nutr, Stippeneng 4, NL-6708 WE Wageningen, Netherlands
[6] Hosp Gelderse Vallei, Dept Geriatr Med, Willy Brandtlaan 10, NL-6716 RP Ede, Netherlands
[7] Univ Hohenheim, Schloss Hohenheim 1, D-70599 Stuttgart, Germany
关键词
Public health; Drug-nutrient interactions; Micronutrient deficiency; Microbiota; Health benefits; POLYUNSATURATED FATTY-ACIDS; MATRIX GLA-PROTEIN; VITAMIN-D SUPPLEMENTATION; PUMP INHIBITOR THERAPY; NEURAL-TUBE DEFECTS; VASCULAR CALCIFICATION; OMEGA-3-FATTY-ACID SUPPLEMENTATION; CARDIOVASCULAR-DISEASE; EICOSAPENTAENOIC ACID; ORAL-CONTRACEPTIVES;
D O I
10.1007/s00394-017-1510-3
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
paper summarizes the proceedings of the symposium and provides an outlook for future research needs and public health measures. Since food, pharma and health are closely interconnected domains, awareness is needed in the medical community about the potential relevance of drug-nutrition interactions. Experts and stakeholders should advocate for the integration of drug-nutrition evaluations in the drug development process. Strategies for the individual patients should be developed, by installing drug review protocols, screening for malnutrition and integrating this topic into the general medical advice. The public health relevance of drug-nutrition interactions is currently highly undervalued and overlooked. This is particularly the case for elderly persons where multi-morbidity and consequently polypharmacy is very common. Vitamins and other micronutrients have central functions in metabolism, and their interactions with drugs may result in clinically relevant physiological impairments but possibly also in positive effects. On 12 April 2016, the University Medical Center Groningen (The Netherlands), as part of its Healthy Ageing program, organized a workshop on the public health relevance of drug-nutrient interactions. In this meeting, experts in the field presented results from recent studies on interactions between pharmaceuticals and nutrients, and discussed the role of nutrition for elderly, focusing on those persons receiving pharmaceutical treatment. This
引用
收藏
页码:S23 / S36
页数:14
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