Type 2 diabetes mellitus: a disease of the innate immune system? An update

被引：126
作者：
Crook, M [1 ]
机构：
[1] Univ Hosp Lewisham, London SE13 6LH, England
来源：
DIABETIC MEDICINE | 2004年 / 21卷 / 03期
关键词：
acute phase response; complications; C-reactive protein; diabetes; inflammation; insulin resistance; sialic acid;
D O I：
10.1046/j.1464-5491.2003.01030.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A few years ago a hypothesis was proposed suggesting that elements of the innate immune system, such as acute phase reactants, contribute to the development of Type 2 diabetes mellitus. Acute phase reactants such as C-reactive protein and sialic acid may thus predict risk of developing Type 2 diabetes mellitus, as well as being markers of diabetes microvascular and macrovascular complications. This article discusses these issues.
引用
收藏
页码：203 / 207
页数：5
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