Rapid SARS-CoV-2 Inactivation in a Simulated Hospital Room Using a Mobile and Autonomous Robot Emitting Ultraviolet-C Light

被引：16

作者：

Lorca-Oro, Cristina ^{[1
]}

Vila, Jordi ^{[2
,3
]}

Pleguezuelos, Patricia ^{[1
]}

Vergara-Alert, Julia ^{[1
]}

Rodon, Jordi ^{[1
]}

Majo, Natalia ^{[1
,4
]}

Lopez, Sergio ^{[1
]}

Segales, Joaquim ^{[1
,4
]}

Saldana-Buesa, Francesc ^{[5
]}

Visa-Boladeras, Maria ^{[6
]}

Vea-Baro, Andreu ^{[2
,5
]}

Maria Campistol, Josep ^{[2
,3
]}

Abad, Xavier ^{[1
]}

机构：

[1] Ctr Recerca Sanitat Anim, Inst Recerca & Tecnol Agroalimentaries, Campus Univ Autonoma Barcelona, Barcelona, Spain

[2] Univ Barcelona, Hosp Clin, August Pi & Sunyer Biomed Res Inst, Barcelona, Spain

[3] Univ Barcelona, Inst Global Hlth ISGlobal Hosp Clin, Barcelona, Spain

[4] Univ Autonoma Barcelona, Fac Vet, Dept Sanitat & Anat Anim, Barcelona, Spain

[5] CovidWarriors, Barcelona, Spain

[6] MTS Tech, Barcelona, Spain

来源：

JOURNAL OF INFECTIOUS DISEASES | 2022年 / 225卷 / 04期

关键词：

SARS-CoV-2; inactivation; UV-C radiation; autonomous robots; exponential viral-load reduction; virus inactivation; CORONAVIRUS;

D O I：

10.1093/infdis/jiab551

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since 2019 has made mask-wearing, physical distancing, hygiene, and disinfection complementary measures to control virus transmission. Especially for health facilities, we evaluated the efficacy of an UV-C autonomous robot to inactivate SARS-CoV-2 desiccated on potentially contaminated surfaces. ASSUM (autonomous sanitary sterilization ultraviolet machine) robot was used in an experimental box simulating a hospital intensive care unit room. Desiccated SARS-CoV-2 samples were exposed to UV-C in 2 independent runs of 5, 12, and 20 minutes. Residual virus was eluted from surfaces and viral titration was carried out in Vero E6 cells. ASSUM inactivated SARS-CoV-2 by >= 99.91% to >= 99.99% titer reduction with 12 minutes or longer of UV-C exposure and onwards and a minimum distance of 100 cm between the device and the SARS-CoV-2 desiccated samples. This study demonstrates that ASSUM UV-C device is able to inactivate SARS-CoV-2 within a few minutes.

引用

页码：587 / 592

页数：6

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