Peri-Pregnancy Cannabis Use and Autism Spectrum Disorder in the Offspring: Findings from the Study to Explore Early Development

被引:8
|
作者
DiGuiseppi, Carolyn [1 ]
Crume, Tessa [1 ]
Van Dyke, Julia [1 ]
Sabourin, Katherine R. [1 ]
Soke, Gnakub N. [2 ]
Croen, Lisa A. [3 ]
Daniels, Julie L. [4 ]
Lee, Li-Ching [5 ]
Schieve, Laura A. [2 ]
Windham, Gayle C. [6 ]
Friedman, Sandra [7 ]
Rosenberg, Cordelia Robinson [7 ]
机构
[1] Univ Colorado, Dept Epidemiol, Colorado Sch Publ Hlth, Anschutz Med Campus,13001 E 17th Pl, Aurora, CO 80045 USA
[2] Ctr Dis Control & Prevent, Natl Ctr Birth Defects & Dev Disabil, Atlanta, GA 30341 USA
[3] Kaiser Permanente Northern Calif, Div Res, Oakland, CA 94612 USA
[4] Univ N Carolina, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27514 USA
[5] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA
[6] Calif Dept Publ Hlth, Environm Hlth Invest Branch, Richmond, CA 94804 USA
[7] Univ Colorado, Dept Pediat, Sch Med, Anschutz Med Campus, Aurora, CO 80045 USA
关键词
Cannabis; Marijuana; Epidemiology; Autism spectrum disorder; EARLY DEVELOPMENT SEED; MARIJUANA USE; CHILDREN; TRENDS; RISK; VALIDITY; EXPOSURE; COHORT; SYSTEM;
D O I
10.1007/s10803-021-05339-4
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
The association of autism spectrum disorder (ASD) with self-reported maternal cannabis use from 3 months pre-conception to delivery ("peri-pregnancy") was assessed in children aged 30-68 months, born 2003 to 2011. Children with ASD (N = 1428) were compared to children with other developmental delays/disorders (DD, N = 1198) and population controls (POP, N = 1628). Peri-pregnancy cannabis use was reported for 5.2% of ASD, 3.2% of DD and 4.4% of POP children. Adjusted odds of peri-pregnancy cannabis use did not differ significantly between ASD cases and DD or POP controls. Results were similar for any use during pregnancy. However, given potential risks suggested by underlying neurobiology and animal models, further studies in more recent cohorts, in which cannabis use and perception may have changed, are needed.
引用
收藏
页码:5064 / 5071
页数:8
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