Simulated moving bed with a product column for improving the separation performance

被引：0
作者：
Kim, Kyung-Min [1 ,2 ]
Han, Kyeong-Woo [1 ,3 ]
Kim, Seung-Ik [1 ]
Bae, Youn-Sang [1 ,3 ]
机构：
[1] Yonsei Univ, Dept Chem & Biomol Engn, 50 Yonsei Ro, Seoul, South Korea
[2] Korea Elect Power Corp Res Inst, Environm & Climate Change Lab, 105 Munji Ro, Daejeon, South Korea
[3] Yonsei Univ, Dept Integrated Engn, 50 Yonsei Ro, Seoul, South Korea
来源：
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY | 2020年 / 88卷
基金：
新加坡国家研究基金会;
关键词：
Simulated moving-bed; SMB; Chromatography; Operating strategy; Performance parameter; PARTIAL-DISCARD STRATEGY; OPERATION; CHROMATOGRAPHY; DESIGN; UNITS; FLOW;
D O I：
10.1016/j.jiec.2020.04.032
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Improving both the purity and recovery of the simulated moving-bed (SMB) chromatography is an important and challenging issue. Therefore, this study presents a novel operation strategy where a part of the SMB product with relatively low purity is retreated in an additional column, named as the product column (PC), for its further purification; this SMB method with PC is called ProductCol. Moreover, design criteria for selecting the operating variables, including flow rate, column length, and adsorbent properties in the PC, are suggested based on the equilibrium theory. Their effects on the separation performance were also investigated. The simulation results showed that the ProductCol process with sufficient flow rates and column lengths could outperform the classical SMB one in terms of purity and recovery. (C) 2020 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：328 / 338
页数：11
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