Induction of a State of Iron Limitation in Uropathogenic Escherichia coli CFT073 by Cranberry-Derived Proanthocyanidins as Revealed by Microarray Analysis

被引：17

作者：

Hidalgo, Gabriela ^{[1
]}

Ponton, Andre ^{[2
,3
]}

Fatisson, Julien ^{[1
]}

O'May, Che ^{[1
]}

Asadishad, Bahareh ^{[1
]}

Schinner, Tim ^{[1
]}

Tufenkji, Nathalie ^{[1
]}

机构：

[1] McGill Univ, Dept Chem Engn, Montreal, PQ H3A 2B2, Canada

[2] McGill Univ, Montreal, PQ H3A 1E4, Canada

[3] Genome Quebec Innovat Ctr, Montreal, PQ H3A 1E4, Canada

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2011年 / 77卷 / 04期

基金：

加拿大自然科学与工程研究理事会;

关键词：

URINARY-TRACT-INFECTIONS; BACTERIAL ADHESION; JUICE; INHIBITION; PREVENTION; EXPRESSION; ADHERENCE; HUMANS;

D O I：

10.1128/AEM.02201-10

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Transcriptional profiles of uropathogenic Escherichia coli CFT073 exposed to cranberry-derived proanthocyanidins (PACs) were determined. Our results indicate that bacteria grown on media supplemented with PACs were iron deprived. To our knowledge, this is the first time that PACs have been shown to induce a state of iron limitation in this bacterium.

引用

页码：1532 / 1535

页数：4

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