Acid catalyzed stereoselective rearrangement and dimerization of flavenes: synthesis of dependensin

被引：46

作者：

Deodhar, Mandar ^{[1
]}

Black, David StC ^{[1
]}

Kumar, Naresh ^{[1
]}

机构：

[1] Univ New S Wales, Sch Chem, Sydney, NSW 2052, Australia

来源：

TETRAHEDRON | 2007年 / 63卷 / 24期

关键词：

dimers; dependensin; acid catalyzed dimerization; benzopyranobenzopyran;

D O I：

10.1016/j.tet.2007.03.173

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Appropriately substituted flavenes undergo stereoselective rearrangement and dimerization when treated with methanolic hydrochloric acid to give benzopyranobenzopyrans. A rationale for the rearrangement is proposed. This synthetic methodology has been used for a high yield synthesis of the natural product dependensin. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：5227 / 5235

页数：9

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