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Zhejiang Univ, Key Lab Canc Prevent & Intervent, Hosp 2, Dept Med Oncol,China Natl Minist Educ,Coll Med, Hangzhou 310009, Zhejiang, Peoples R China Zhejiang Univ, Key Lab Canc Prevent & Intervent, Hosp 2, Dept Med Oncol,China Natl Minist Educ,Coll Med, Hangzhou 310009, Zhejiang, Peoples R China