Neuromyelitis Optica Spectrum Disorder With Hyponatremia as an Initial Presentation: A Case Report

被引：1
|
作者：
Yang, Siqi [1 ,2 ]
Tian, Juan [1 ]
Huang, Hui [1 ]
Yan, Zhe [1 ]
机构：
[1] Sichuan Univ, West China Hosp, Dept Endocrinol & Metab, 37 Guo Xue Lane, Chengdu 610041, Sichuan, Peoples R China
[2] Sichuan Univ, West China Sch Med, Chengdu, Peoples R China
来源：
CLINICAL THERAPEUTICS | 2021年 / 43卷 / 12期
关键词：
aquaporin; 4; case report; hyponatremia; myelitis; optic neuritis; ANTIDIURETIC-HORMONE SECRETION;
D O I：
10.1016/j.clinthera.2021.10.001
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The diagnosis of neuromyelitis optica spectrum disorder (NMOSD) is easily missed or delayed because of its multiple clinical features, especially at initial presentation. Hyponatremia is an infrequent complication of NMOSD and can present as an initial sign. Hyponatremia in a patient with NMOSD might be caused by autoimmune-related antibodies that attack the hypothalamus, causing inappropriate antidiuretic hormone secretion. Awareness of this pathophysiologic mechanism will help clinicians in the early diagnosis of NMOSD. We report a case of NMOSD with hyponatremia as the initial presentation. (Clin Ther. 2021;43:2168-2172.) (c) 2021 Elsevier Inc.
引用
收藏
页码：2168 / 2172
页数：5
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