Sonochemical synthesis of deep eutectic solvent-coated magnetic nanoparticles and their application in magnetic dispersive micro solid phase extraction-dispersive liquid-liquid microextraction of polycyclic aromatic hydrocarbons from mascara

In this study, application of magnetic dispersive micro solid phase extraction of polycyclic aromatic hydrocarbons from mascara was reported. The extracted analytes were concentrated by a dispersive liquid-liquid microextraction procedure to reach high enrichment factors and low detection limits. In this work, deep eutectic solvent-coated iron nanoparticles were synthesized sonochemically and characterized by energy-dispersive X-ray spectroscopy, scanning electron microscopy, Furrier transform infrared spectrometry, and vibrating sample magnetometry. The extraction procedure was done by extracting the analytes from mascara into an aqueous solution composed of methanol and deionized water. Then the sorbent was added into the solution and the mixture was vortexed. After that the sorbent was separated from the aqueous solution and the analytes were desorbed by methanol with the aid of vortexing. Whole of the elution solvent was collected and mixed with carbon tetrachloride and dispersed into sodium chloride solution. Validation data showed that limits of detection and quantification were within the ranges of 0.33-0.57 and 1.1-1.9 ng/g, respectively. Relative standard deviation values were <= 8.6%. The extraction recovery values were in the range of 80-95%. The new method was successfully used for the analysis of the studied compounds in five mascara samples and three analytes were detected in all samples at ng/g level.