共 32 条
The increased recurrence rate of liver abscess caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae
被引:16
作者:

Wang, Hairui
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机构:
China Med Univ, Dept Radiol, Shengjing Hosp, 36 Sanhao St, Shenyang 110004, Peoples R China China Med Univ, Dept Radiol, Shengjing Hosp, 36 Sanhao St, Shenyang 110004, Peoples R China

Ren, Yue
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机构:
China Med Univ, Dept Radiol, Shengjing Hosp, 36 Sanhao St, Shenyang 110004, Peoples R China China Med Univ, Dept Radiol, Shengjing Hosp, 36 Sanhao St, Shenyang 110004, Peoples R China

Chang, Zhihui
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机构:
China Med Univ, Dept Radiol, Shengjing Hosp, 36 Sanhao St, Shenyang 110004, Peoples R China China Med Univ, Dept Radiol, Shengjing Hosp, 36 Sanhao St, Shenyang 110004, Peoples R China

Liu, Zhaoyu
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机构:
China Med Univ, Dept Radiol, Shengjing Hosp, 36 Sanhao St, Shenyang 110004, Peoples R China China Med Univ, Dept Radiol, Shengjing Hosp, 36 Sanhao St, Shenyang 110004, Peoples R China
机构:
[1] China Med Univ, Dept Radiol, Shengjing Hosp, 36 Sanhao St, Shenyang 110004, Peoples R China
基金:
中国国家自然科学基金;
关键词:
Klebsiella pneumonia;
Liver abscess;
Extended-spectrum beta-lactamase (ESBL);
Recurrence;
CT CHARACTERISTICS;
RISK-FACTORS;
INFECTIONS;
EPIDEMIOLOGY;
ASSOCIATION;
MORTALITY;
FEATURES;
IMPACT;
D O I:
10.1007/s10096-020-03848-1
中图分类号:
R51 [传染病];
学科分类号:
100401 ;
摘要:
The pathogenic bacterium Klebsiella pneumoniae (KP) is the major causative agent of pyogenic liver abscess (PLA). But reports about the prognosis of KP-caused PLA (KPLA) are rare. This study aimed to ascertain the recurrence rate of KPLA after initial treatment and its contributing factors. A total of 110 patients who had first-time episodes of KPLA were included into the study. The average follow-up time was 3.65 +/- 2.18 years. Twenty (18.18%) KPLA patients experienced recurrence. Those in the recurrence group had a significantly greater incidence of extended-spectrum beta-lactamase (ESBL) production compared with the non-recurrence group (30.0% vs 8.89%, P = 0.018). Diabetes, biliary tract disease, and history of malignancy were not associated with recurrence (all P > 0.05). No difference in the CT characteristics of KPLA (including abscess size, location, whether multilocular, gas production of KPLA, and thrombophlebitis) was found between the two groups. Multivariate regression analysis showed that ESBL production (OR, 6.3; 95% CI, 1.02-38.59; P = 0.04) was an independent risk factor for the recurrence of KPLA. Our findings emphasize that KPLA has a high recurrence rate and ESBL production is an independent risk factor for recurrent KPLA.
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页码:1315 / 1320
页数:6
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Yang, Tian-Ci
;
Li, Shu-Lian
;
Niu, Jian-Jun
.
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE,
2017, 11
:23-27

Deng, Jie
论文数: 0 引用数: 0
h-index: 0
机构:
Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China
Fujian Med Univ, Xiamen Zhongshan Hosp, Xiamen, Peoples R China Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China

Li, Yan-Ting
论文数: 0 引用数: 0
h-index: 0
机构:
Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China

Shen, Xu
论文数: 0 引用数: 0
h-index: 0
机构:
Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China
Fujian Med Univ, Xiamen Zhongshan Hosp, Xiamen, Peoples R China Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China

Yu, Yi-Wen
论文数: 0 引用数: 0
h-index: 0
机构:
Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China

Lin, Hui-Ling
论文数: 0 引用数: 0
h-index: 0
机构:
Xiamen Huli Dist Matern & Child Care Hosp, Xiamen, Peoples R China Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China

Zhao, Qi-Feng
论文数: 0 引用数: 0
h-index: 0
机构:
Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China
Fujian Med Univ, Xiamen Zhongshan Hosp, Xiamen, Peoples R China Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China

Yang, Tian-Ci
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h-index: 0
机构:
Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China

Li, Shu-Lian
论文数: 0 引用数: 0
h-index: 0
机构:
Xiamen Huli Dist Matern & Child Care Hosp, Xiamen, Peoples R China Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China

Niu, Jian-Jun
论文数: 0 引用数: 0
h-index: 0
机构:
Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China
Fujian Med Univ, Xiamen Zhongshan Hosp, Xiamen, Peoples R China Xiamen Univ, Med Coll, Zhongshan Hosp, Xiamen, Peoples R China