Effect and safety of tamsulosin, the prostate specific alpha(1)-blocker, in the treatment of BPH (benign prostatic hyperplasia)

被引：2
作者：
Kawabe, K
机构：
[1] Department of Urology, Faculty of Medicine, The University of Tokyo, Tokyo
来源：
AKTUELLE UROLOGIE | 1996年 / 27卷
关键词：
BPH; alpha-blocker; alpha(1a)-receptor-subtype; tamsulosin;
D O I：
10.1055/s-2008-1055642
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Clinical trials of tamsulosin demonstrate that it is an effective treatment modality for the symptoms associated with BPH, and it has practically no effect on blood pressure at a dose of 0.2 mg. This is probably due to its selective affinity for the prostate, which may be due to the strong affinity of tamsulosin for the alpha(1a)-receptor subtype.
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页码：25 / 26
页数：2
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