Effect and safety of tamsulosin, the prostate specific alpha(1)-blocker, in the treatment of BPH (benign prostatic hyperplasia)

被引:2
作者
Kawabe, K
机构
[1] Department of Urology, Faculty of Medicine, The University of Tokyo, Tokyo
关键词
BPH; alpha-blocker; alpha(1a)-receptor-subtype; tamsulosin;
D O I
10.1055/s-2008-1055642
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Clinical trials of tamsulosin demonstrate that it is an effective treatment modality for the symptoms associated with BPH, and it has practically no effect on blood pressure at a dose of 0.2 mg. This is probably due to its selective affinity for the prostate, which may be due to the strong affinity of tamsulosin for the alpha(1a)-receptor subtype.
引用
收藏
页码:25 / 26
页数:2
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