Evolutionary crossroads in developmental biology: Dictyostelium discoideum

被引：65
作者：
Schaap, Pauline [1 ]
机构：
[1] Univ Dundee, Coll Life Sci, Dundee DD1 5EH, Scotland
来源：
DEVELOPMENT | 2011年 / 138卷 / 03期
基金：
英国惠康基金; 英国生物技术与生命科学研究理事会;
关键词：
Evolution of multicellularity; Social amoeba; Encystation; Sporulation; Dictyostelium; DEPENDENT PROTEIN-KINASE; DIFFERENTIATION-INDUCING FACTOR; ADENYLYL-CYCLASE-G; SOCIAL AMEBAS; TERMINAL DIFFERENTIATION; CELL-DIFFERENTIATION; GENE-EXPRESSION; CYCLIC-AMP; PRESPORE DIFFERENTIATION; MOLECULAR PHYLOGENY;
D O I：
10.1242/dev.048934
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Dictyostelium discoideum belongs to a group of multicellular life forms that can also exist for long periods as single cells. This ability to shift between uni- and multicellularity makes the group ideal for studying the genetic changes that occurred at the crossroads between uni- and multicellular life. In this Primer, I discuss the mechanisms that control multicellular development in Dictyostelium discoideum and reconstruct how some of these mechanisms evolved from a stress response in the unicellular ancestor.
引用
收藏
页码：387 / 396
页数：10
相关论文
共 85 条
[81]  
West CM, 2003, INT REV CYTOL, V222, P237
[82]   Transcriptional regulation of Dictyostelium pattern formation [J].
Williams, JG .
EMBO REPORTS, 2006, 7 (07) :694-698
[83]   Towards a molecular understanding of human diseases using Dictyostelium discoideum [J].
Williams, Robin S. B. ;
Boeckeler, Katrina ;
Graef, Ralph ;
Mueller-Taubenberger, Annette ;
Li, Zhiru ;
Isberg, Ralph R. ;
Wessels, Deborah ;
Soll, David R. ;
Alexander, Hannah ;
Alexander, Stephen .
TRENDS IN MOLECULAR MEDICINE, 2006, 12 (09) :415-424
[84]   Spatiotemporal Regulation of Ras Activity Provides Directional Sensing [J].
Zhang, Sheng ;
Charest, Pascale G. ;
Firtel, Richard A. .
CURRENT BIOLOGY, 2008, 18 (20) :1587-1593
[85]   The hybrid histidine kinase dhkB regulates spore germination in Dictyostelium discoideum [J].
Zinda, MJ ;
Singleton, CK .
DEVELOPMENTAL BIOLOGY, 1998, 196 (02) :171-183
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