A new phenylethanoid glycoside from Incarvillea compacta

被引:3
作者
Wu, Hai-Feng [1 ,2 ]
Zhu, Yin-Di [1 ,2 ]
Zhang, Li-Jing [1 ,2 ]
Zou, Qiong-Yu [3 ]
Chen, Li [1 ,2 ,3 ]
Shen, Ting [4 ]
Wang, Xin-Feng [4 ]
Ma, Guo-Xu [1 ,2 ]
Hu, Bo-Ran [5 ]
Hu, Wei-Cheng [4 ]
Xu, Xu-Dong [1 ,2 ]
机构
[1] Peking Union Med Coll, Inst Med Plant Dev, Minist Educ, Key Lab Bioact Subst & Resources Utilizat Chinese, Beijing 100193, Peoples R China
[2] Chinese Acad Med Sci, Beijing 100193, Peoples R China
[3] Huaihua Univ, Dept Chem & Chem Engn, Key Lab Hunan Prov Study & Utilizat Ethn Med Plan, Huaihua 418008, Peoples R China
[4] Huaiyin Normal Univ, Jiangsu Collaborat Innovat Ctr Reg Modern Agr & E, Jiangsu Key Lab Ecoagr Biotechnol Hongze Lake, Huaian, Peoples R China
[5] Yangzhou Univ, Coll Food Sci & Engn, Yangzhou 225001, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
Bignoniaceae; Incarvillea compacta; hepatoprotective effect; antioxidant activity; phenylethanoid glycoside; 3 '''-O-methylcampneoside I; SESQUITERPENOIDS; ARGUTA;
D O I
10.1080/10286020.2015.1096931
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A new phenylethanoid glycoside, 3 '''-O-methylcampneoside I (1), was isolated from the 90% ethanolic extract of the roots of Incarvillea compacta, together with three known compounds, campneoside I (2), ilicifolioside A (3), and campneoside II (4). Their structures were determined spectroscopically and compared with previously reported spectral data. Compound 1 existed as epimers and displayed better 1,1-diphenyl-2-picrylhydrazyl (DPPH)-free radical scavenging activity using di-tert-butyl-4-methylphenol (BHT) as the positive control. In addition, pretreatment of human HepG2 cells with compound 1 significantly increased the viability on CCl4-induced cell death.
引用
收藏
页码:596 / 602
页数:7
相关论文
共 16 条
  • [1] A monoterpene alkaloid from Incarvillea sinensis
    Chi, YM
    Nakamura, M
    Zhao, XY
    Yoshizawa, T
    Yan, WM
    Hashimoto, F
    Kinjo, J
    Nohara, T
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 2005, 53 (09) : 1178 - 1179
  • [2] Delectis Florae Reipublicae Popularis Sinicae Agendae Academiae Sinicae Edita (Editorial Committee of Flora of China), 1990, FLOR REP POP SIN, P46
  • [3] Naturally Occurring Phenylethanoid Glycosides: Potential Leads for New Therapeutics
    Fu, Guangmiao
    Pang, Haihong
    Wong, Yung H.
    [J]. CURRENT MEDICINAL CHEMISTRY, 2008, 15 (25) : 2592 - 2613
  • [4] Two novel monoterpene alkaloid dimers from Incarvillea arguta
    Fu, Jian-Jun
    Jin, Hui-Zi
    Shen, Yun-Heng
    Zhang, Wei-Dong
    Xu, Wen-Zheng
    Zeng, Qi
    Yan, Shi-Kai
    [J]. HELVETICA CHIMICA ACTA, 2007, 90 (11) : 2151 - 2155
  • [5] Four New Sesquiterpenoids from the Roots of Incarvillea arguta and Their Inhibitory Activities against Lipopolysaccharide-Induced Nitric Oxide Production
    Fu, Jian-Jun
    Qin, Jiang-Jiang
    Zeng, Qi
    Huang, Ying
    Jin, Hui Zi
    Zhang, Wei-Dong
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 2010, 58 (09) : 1263 - 1266
  • [6] Neuroprotective effects of macranthoin G from Eucommia ulmoides against hydrogen peroxide-induced apoptosis in PC12 cells via inhibiting NF-κB activation
    Hu, Weicheng
    Wang, Gongcheng
    Li, Pengxia
    Wang, Yuning
    Si, Chuan-Ling
    He, Jing
    Long, Wei
    Bai, Yujia
    Feng, Zuoshan
    Wang, Xinfeng
    [J]. CHEMICO-BIOLOGICAL INTERACTIONS, 2014, 224 : 108 - 116
  • [7] BITTER PHENYL PROPANOID GLYCOSIDES FROM CAMPSIS-CHINENSIS
    IMAKURA, Y
    KOBAYASHI, S
    MIMA, A
    [J]. PHYTOCHEMISTRY, 1985, 24 (01) : 139 - 146
  • [8] Lu Longhai, 2009, Zhongguo Zhong Yao Za Zhi, V34, P1799
  • [9] A new iridoid from Incarvillea delavayi
    Lu, Tao
    Zhang, Wei Dong
    Pei, Yue Hu
    Zhang, Chuan
    Li, Jin Cheng
    Shen, Yun Heng
    [J]. CHINESE CHEMICAL LETTERS, 2007, 18 (12) : 1512 - 1514
  • [10] Studies on the phenylethanoid glycosides with anti-complement activity from Paulownia tomentosa var. tomentosa wood
    Si, Chuan-Ling
    Deng, Xiao-Juan
    Liu, Zhong
    Kim, Jin-Kyu
    Bae, Young-Soo
    [J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2008, 10 (11) : 1003 - 1008