Human and animal dietary exposure to T-2 and HT-2 toxin

被引:106
作者
Arcella, Davide
Gergelova, Petra
Innocenti, Matteo Lorenzo
Steinkellner, Hans
机构
关键词
T-2; HT-2; food; feed; dietary exposure; MYCOTOXINS; OATS;
D O I
10.2903/j.efsa.2017.4972
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
T-2 toxin (T2) and HT-2 (HT2) toxin are trichothecenes, which form part of the group of Fusarium mycotoxins. Food and feed samples used to estimate human dietary and animal exposure were reported either as the individual results for T2 and/or, HT2, and/or as the sum of the two. The highest concentrations were reported in oats and oat-containing commodities. Very high levels were reported in a small number of data on specific plant- and herb-based dietary supplements. In humans, the mean chronic dietary exposure to the sum of T2 and HT2 was highest in Toddlers' and Infants', with maximum upper bound (UB) estimates of 64.8 and 62.9ng/kg body weight (bw) per day, respectively. The 95th percentile dietary exposure was highest in Infants' with a maximum UB estimate of 146ng/kg bw per day. UB estimations were on average fourfold higher than lower bound (LB) estimations. Average acute exposure ranged from a minimum of 13.4ng/kg bw per day, estimated in Elderly', up to a maximum of 64.7ng/kg bw per day estimated in Toddlers'. The highest 95th percentile acute dietary exposure was estimated for a dietary survey within the age class Infants' (170ng/kg bw per day). Overall, among processed foods the main contributors were cereal flakes, fine bakery wares and, for acute exposure, also bread and rolls. In the elderly and very elderly, dietary supplements made an important contribution. Exposure to the sum of T2 and HT2 in farm and companion animals varied according to the animal species. Exposures considering mean concentration scenarios varied between 0.03-0.08 (LB-UB) g/kg bw per day in beef cattle and 1.13-1.47g/kg bw per day in milking goats. For high concentration scenarios, exposures varied between 0.12-0.16g/kg bw per day and 2.37-2.58g/kg bw per day in the same species. In the absence of data, potential modified form were not included.
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页数:57
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共 26 条
  • [1] AFSSA, 2009, EV RISQ LIES PRES MY
  • [2] Scientific Opinion on Dietary Reference Values for carbohydrates and dietary fibre
    Agostoni, Carlo
    Bresson, Jean-Louis
    Fairweather-Tait, Susan
    Flynn, Albert
    Golly, Ines
    Korhonen, Hannu
    Lagiou, Pagona
    Lovik, Martinus
    Marchelli, Rosangela
    Martin, Ambroise
    Moseley, Bevan
    Neuhaeuser-Berthold, Monika
    Przyrembel, Hildegard
    Salminen, Seppo
    Sanz, Yolanda
    Strain, Sean
    Strobel, Stephan
    Tetens, Inge
    Tome, Daniel
    van Loveren, Hendrik
    Verhagen, Hans
    [J]. EFSA JOURNAL, 2010, 8 (03)
  • [3] Alderman G., 1993, Energy and protein requirements of ruminants: an advisory manual
  • [5] [Anonymous], 2007, Nutrient requirements of small ruminants, DOI DOI 10.17226/11654
  • [6] Guidance of the Scientific Committee on a request from EFSA related to Uncertainties in Dietary Exposure Assessment Request No EFSA-Q-2004-019 Adopted on 14 December 2006
    Barlow, Sue
    Chesson, Andrew
    Collins, John
    Dybing, Erik
    Flynn, Albert
    Fruijtier-Polloth, Claudia
    Hardy, Tony
    Knaap, Ada
    Kuiper, Harry
    Le Neindre, Pierre
    Schans, Jan
    Schlatter, Josef
    Silano, Vittorio
    Skerving, Steffan
    Vannier, Philippe
    [J]. EFSA JOURNAL, 2007, 5 (01)
  • [7] Scientific Opinion on the risks for human and animal health related to the presence of modified forms of certain mycotoxins in food and feed
    Benford, Diane
    Ceccatelli, Sandra
    Cottrill, Bruce
    DiNovi, Michael
    Dogliotti, Eugenia
    Edler, Lutz
    Farmer, Peter
    Fuerst, Peter
    Hoogenboom, Laurentius
    Knutsen, Helle Katrine
    Lundebye, Anne-Katrine
    Metzler, Manfred
    Mutti, Antonio
    Nebbia, Carlo Stefano
    O'Keeffe, Michael
    Petersen, Annette
    Rietjens, Ivonne
    Schrenk, Dieter
    Silano, Vittorio
    van Loveren, Hendrik
    Vleminckx, Christiane
    Wester, Pieter
    [J]. EFSA JOURNAL, 2014, 12 (12)
  • [8] Carabano R., 1998, P1
  • [9] Management of left-censored data in dietary exposure assessment of chemical substances
    European Food Safety Authority
    [J]. EFSA JOURNAL, 2010, 8 (03)