Diffuse large B cell lymphoma-related prognostic factors, Ki-67 and Bcl-6 expression levels.

被引：0

作者：

Xie, Rong ^{[1
]}

Tang, Jing ^{[1
]}

Hu, Sheng ^{[1
]}

Jiang, Hui ^{[1
]}

机构：

[1] Hubei Canc Hosp, Dept Oncol, Wuhan, Hubei, Peoples R China

来源：

BIOMEDICAL RESEARCH-INDIA | 2017年 / 28卷 / 15期

关键词：

Diffuse large B cell lymphoma (DLBCL); Prognosis; Bcl-6; Ki-67; ANTITUMOR-ACTIVITY; NANOPARTICLES; DELIVERY; DRUG;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Objective: This study aims to investigate the diffuse large B cell lymphoma-related prognostic factors, Bcl-6 and Ki-67 expression levels. Methods: 67 cases of patients with diffuse large B cell lymphoma in our hospital were collected from Feb 2014 to Mar 2015. The Bcl-6 and Ki-67 expression levels in patients with diffuse large B cell lymphoma were detected using the immunohistochemical method. The related characteristics and prognosis were analyzed. Results: Statistical analysis shows that the Bcl-6 protein expression levels are not related to sex or age; Ki-67 is not related to sex but related to age. Bcl-6 is not related to lactate dehydrogenase or primary site but is related to Ann Arbor stage. Ki-67 is related to lactate dehydrogenase and Ann Arbor stage. Conclusion: The microvessel density dose, Bcl-6-positive rate and Ki-67 labelling index of diffuse large B cell lymphoma are important indexes to evaluate the prognosis of patients with diffuse large B cell lymphoma.

引用

页码：6740 / 6742

页数：3

共 10 条

[1] Delivery of Nanoparticles for Treatment of Brain Tumor
Kang, Chen
Sun, Yuan
Zhu, Jing
Li, Wen
Zhang, Aili
Kuang, Tairong
Xie, Jing
Yang, Zhaogang
[J]. CURRENT DRUG METABOLISM, 2016, 17 (08) : 745 - 754
[2] Photo-crosslinking of a self-assembled coumarin-dipeptide hydrogel
Kim, Se Hye
Sun, Yuan
Kaplan, Jonah A.
Grinstaff, Mark W.
Parquette, Jon R.
[J]. NEW JOURNAL OF CHEMISTRY, 2015, 39 (05) : 3225 - 3228
[3] The Self-Assembly of Anticancer Camptothecin-Dipeptide Nanotubes: A Minimalistic and High Drug Loading Approach to Increased Efficacy
Kim, Se Hye
Kaplan, Jonah A.
Sun, Yuan
Shieh, Aileen
Sun, Hui-Lung
Croce, Carlo M.
Grinstaff, Mark W.
Parquette, Jon R.
[J]. CHEMISTRY-A EUROPEAN JOURNAL, 2015, 21 (01) : 101 - 105
[4] Li J, 2016, LAT AM J PHARM, V35, P1559
[5] Nisar N, 2013, LAT AM J PHARM, V32, P322
[6] Ozturk N, 2017, LAT AM J PHARM, V36, P44
[7] Raj JR, 2016, BIOMED RES-INDIA, V27, P596
[8] Saileshl KS, 2016, BIOMED RES-INDIA, V27, P611
[9] Crocetin Inhibits Lipopolysaccharide-Induced Inflammatory Response in Human Umbilical Vein Endothelial Cells
Song, Lei
Kang, Chen
Sun, Yuan
Huang, Wenrui
Liu, Wei
Qian, Zhiyu
[J]. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 40 (3-4) : 443 - 452
[10] Delivery of Antipsychotics with Nanoparticles
Sun, Yuan
Kang, Chen
Liu, Fei
Song, Lei
[J]. DRUG DEVELOPMENT RESEARCH, 2016, 77 (07) : 393 - 399

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