Synthesis and characterization of polyester dendrimers from acetoacetate and acrylate

被引：17

作者：

Hirayama, Y

Nakamura, T

Uehara, S

Sakamoto, Y

Yamaguchi, K

Sei, Y

Iwamura, M

机构：

[1] Toho Univ, Dept Biomol Sci, Funabashi, Chiba 2748510, Japan

[2] Toho Univ, Sch Pharmaceut Sci, Funabashi, Chiba 2748510, Japan

[3] Chiba Univ, Ctr Chem Anal, Inage Ku, Chiba 2638522, Japan

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 04期

关键词：

D O I：

10.1021/ol0482184

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New aliphatic polyester-type dendrimers were synthesized using a new AB(2)-type building block 3, prepared from benzyl acetoacetate and 2 equiv of tert-butyl acrylate by acelloacetic acid ester synthesis. The reiterative [deprotection by HCO2H, then EDCI/DMAP coupling] sequence using divergent growth method gave [G1]-4tBu-[G5]-64tBu dendrimers. C-13 NMR relaxation time (T-1) measurements on the carboxy carbons show that the extended chain conformations are predominant in CDCl3.

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页码：525 / 528

页数：4

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