Spontaneous proximal deep vein thrombosis in a patient with severe haemophilia A

被引:22
作者
Dargaud, Y
Cruchaudet, BB
Lienhart, A
Coppéré, B
Ninet, J
Négrier, C
机构
[1] Hop Edouard Herriot, Ctr Reg Traitment Hemophilie, F-69437 Lyon 03, France
[2] Hop Edouard Herriot, Serv Urgences Med, Unite N3, F-69437 Lyon 03, France
[3] Hop Edouard Herriot, Serv Med Interne, F-69437 Lyon 03, France
关键词
haemophilia; deep vein thrombosis; HIV infection;
D O I
10.1097/00001721-200306000-00013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Venous thrombosis is a very rare occurrence in patients with haemophilia A. The majority of these cases occurred during or after the administration of clotting factor concentrates. We report the case of a patient with severe haemophilia A, who spontaneously developed a deep venous thrombosis (DVT). The thrombosis occurred in the superficial femoral vein with an extension in the profunda femoris vein. Neither any local anatomic compression nor any predisposing thrombophilic risk factors were identified. Treatment with recombinant factor VIII at prophylactic doses associated with unfractionated heparin led to a successful resolution. This case illustrates the possibility for severe haemophilia patients to develop authentic spontaneous DVT without anti-haemophilic treatment and predisposing risk factors. (C) 2003 Lippincott Williams Wilkins.
引用
收藏
页码:407 / 409
页数:3
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