SYNTHESIS AND FREE RADICAL SCAVENGING PROPERTY OF SOME QUINOLINE DERIVATIVES

被引：14
|
作者：
Subashini, R. [1 ]
Roopan, S. Mohana [1 ]
Khan, F. Nawaz [1 ]
机构：
[1] VIT Univ, Organ & Med Chem Res Lab, Div Organ Chem, Sch Adv Sci, Vellore 632014, Tamil Nadu, India
来源：
JOURNAL OF THE CHILEAN CHEMICAL SOCIETY | 2010年 / 55卷 / 03期
关键词：
Quinoline derivatives; antioxidant; DPPH method;
D O I：
10.4067/S0717-97072010000300008
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In the present work synthesis of 2-chloroquinoline-3-carbaldehydes (1a-g), 2-chloro-3-(1, 3-dioxolan-2-yl)quinolines (2a-g) and antioxidant activity using the DPPH assays is reported. The results showed that the compounds 1b, 1c, 2b, 2e, 2f possessed 84.65 to 85.75 % radical scavenging activity where as compound 1g showing 92.96% radical scavenging activity.
引用
收藏
页码：317 / 319
页数：3
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