Salivary Gland Branching Morphogenesis - Recent Progress and Future Opportunities

被引:40
作者
Hsu, Jeff Chi-Feng [1 ]
Yamada, Kenneth M. [1 ]
机构
[1] Natl Inst Dent & Craniofacial Res, NIH, Lab Cell & Dev Biol, Bethesda, MD 20892 USA
关键词
salivary gland; epithelium; branching morphogenesis; fibronectin; E-cadherin; growth factor; EMBRYONIC SUBMANDIBULAR-GLAND; GROWTH-FACTOR RECEPTOR; EPITHELIAL MORPHOGENESIS; E-CADHERIN; GENE-EXPRESSION; CELL; EGF; MICE; LOCALIZATION; INVOLVEMENT;
D O I
10.4248/IJOS10042
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Salivary glands provide saliva to maintain oral health, and a loss of salivary gland function substantially decreases quality-of-life. Understanding the biological mechanisms that generate salivary glands during embryonic development may identify novel ways to regenerate function or design artificial salivary glands. This review article summarizes current research on the process of branching morphogenesis of salivary glands, which creates gland structure during development. We highlight exciting new advances and opportunities in studies of cell-cell interactions, mechanical forces, growth factors, and gene expression patterns to improve our understanding of this important process.
引用
收藏
页码:117 / 126
页数:10
相关论文
共 50 条
[31]   Primary Cilia Regulate Branching Morphogenesis during Mammary Gland Development [J].
McDermott, Kimberly M. ;
Liu, Bob Y. ;
Tisty, Thea D. ;
Pazour, Gregory J. .
CURRENT BIOLOGY, 2010, 20 (08) :731-737
[32]   3D Organoid Culture From Adult Salivary Gland Tissues as an ex vivo Modeling of Salivary Gland Morphogenesis [J].
Kim, Donghyun ;
Yoon, Yeo-Jun ;
Choi, Dojin ;
Kim, Jisun ;
Lim, Jae-Yol .
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 9
[33]   miR-200c regulates FGFR-dependent epithelial proliferation via Vldlr during submandibular gland branching morphogenesis [J].
Rebustini, Ivan T. ;
Hayashi, Toru ;
Reynolds, Andrew D. ;
Dillard, Melvin L. ;
Carpenter, Ellen M. ;
Hoffman, Matthew P. .
DEVELOPMENT, 2012, 139 (01) :191-202
[34]   Controlling branching structure formation of the salivary gland by the degree of chitosan deacetylation [J].
Hsiao, Ya-Chuan ;
Chen, Chun-Nan ;
Chen, Yoy-Tzung ;
Yang, Tsung-Lin .
ACTA BIOMATERIALIA, 2013, 9 (09) :8214-8223
[35]   Cellular Dynamics of Epithelial Clefting During Branching Morphogenesis of the Mouse Submandibular Gland [J].
Kadoya, Yuichi ;
Yamashina, Shohei .
DEVELOPMENTAL DYNAMICS, 2010, 239 (06) :1739-1747
[36]   Branching morphogenesis of the mouse mammary gland after exposure to benzophenone-3 [J].
Schierano-Marotti, Gonzalo ;
Altamirano, Gabriela A. ;
Oddi, Sofia ;
Gomez, Ayelen L. ;
Meyer, Nicole ;
Munoz-de-Toro, Monica ;
Zenclussen, Ana C. ;
Rodriguez, Horacio A. ;
Kass, Laura .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2024, 484
[37]   The specificity of chitosan in promoting branching morphogenesis of progenitor salivary tissue [J].
Yang, Tsung-Lin ;
Young, Tai-Horng .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 381 (04) :466-470
[38]   The impact of compositional topography of amniotic membrane scaffold on tissue morphogenesis of salivary gland [J].
Hsiao, Ya-Chuan ;
Lee, Hao-Wei ;
Chen, You-Tzung ;
Young, Tai-Horng ;
Yang, Tsung-Lin .
BIOMATERIALS, 2011, 32 (19) :4424-4432
[39]   Renal branching morphogenesis: concepts, questions, and recent advances [J].
Costantini, Frank .
DIFFERENTIATION, 2006, 74 (07) :402-421
[40]   BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling [J].
Grishina, IB ;
Kim, SY ;
Ferrara, C ;
Makarenkova, HP ;
Walden, PD .
DEVELOPMENTAL BIOLOGY, 2005, 288 (02) :334-347