Processing of affective and emotionally neutral tactile stimuli in the insular cortex

被引:27
作者
Davidovic, Monika [1 ]
Starck, Goran [2 ,3 ]
Olausson, Hakan [1 ,4 ]
机构
[1] Univ Gothenburg, Inst Neurosci & Physiol, Gothenburg, Sweden
[2] Univ Gothenburg, Dept Radiat Phys, Inst Clin Sci, Gothenburg, Sweden
[3] Sahlgrens Univ Hosp, Dept Med Phys & Biomed Engn, Gothenburg, Sweden
[4] Linkoping Univ, CSAN, Linkoping, Sweden
关键词
Touch; fMRI; Insula; Resting state networks; TOUCH; AFFERENTS; PLEASANTNESS; INTEROCEPTION; CONNECTIVITY; TRAJECTORIES; ORGANIZATION; RESPONSES; SYSTEM; FMRI;
D O I
10.1016/j.dcn.2017.12.006
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
The insula is important for the processing of pleasant aspects of touch whereas its role in the processing of emotionally neutral touch has been less explored. Here, we used a network approach to investigate the insular processing of pleasant stroking touch and emotionally neutral vibratory touch, analysing functional magnetic resonance imaging data from 23 healthy adult participants. Vibration and skin stroking activated areas in the posterior, middle and anterior insula. Psychophysiological interaction analyses suggested that skin stroking increased functional connectivity between the posterior and ventral anterior insula. Vibration instead increased functional connectivity between the posterior and dorsal anterior insula, and induced a stronger decrease of the default mode network activity compared to stroking. These results confirmed findings from previous studies showing that the posterior insula processes affective touch information. We suggest that this is accomplished by relaying tactile information from the posterior insula to ventral anterior insula, an area tightly connected to the emotional parts of the brain. However, our results also suggested that the insula processes tactile information with less emotional valence. A central hub in this processing seemed to be the right dorsal anterior insula.
引用
收藏
页码:94 / 103
页数:10
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