Functional interactions of the inferior frontal cortex during the processing of words and word-like stimuli

被引：172

作者：

Bokde, ALW

Tagamets, MA

Friedman, RB

Horwitz, B ^{[1
]}

机构：

[1] Natl Inst Deafness & Other Commun Disorders, Language Sect, NIH, Bethesda, MD 21228 USA

[2] NIMH, Geriatr Psychiat Branch, NIH, Bethesda, MD 20892 USA

[3] Univ Maryland, Sch Med, Maryland Psychiat Res Ctr, Funct Neuroimaging Lab, Baltimore, MD 21201 USA

[4] Georgetown Univ, Med Ctr, Dept Neurol, Washington, DC 20007 USA

[5] NRH Res Ctr, Washington, DC 20007 USA

来源：

NEURON | 2001年 / 30卷 / 02期

关键词：

D O I：

10.1016/S0896-6273(01)00288-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The hypothesis that ventral/anterior left inferior frontal gyrus (LIFG) subserves semantic processing and dorsal/posterior LIFG subserves phonological processing was tested by determining the pattern of functional connectivity of these regions with regions in left occipital and temporal cortex during the processing of words and word-like stimuli. In accordance with the hypothesis, we found strong functional connectivity between activity in ventral LIFG and activity in occipital and temporal cortex only for words, and strong functional connectivity between activity in dorsal LIFG and activity in occipital and temporal cortex for words, pseudowords, and letter strings, but not for false font strings. These results demonstrate a task-dependent functional fractionation of the LIFG in terms of its functional links with posterior brain areas.

引用

页码：609 / 617

页数：9

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