Peptide based biosensors

被引:96
|
作者
Karimzadeh, Ayub [1 ]
Hasanzadeh, Mohammad [2 ]
Shadjou, Nasrin [3 ]
de la Guardia, Miguel [4 ]
机构
[1] Tabriz Univ Med Sci, Pharmaceut Anal Res Ctr, Tabriz 51664, Iran
[2] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz 51664, Iran
[3] Urmia Univ, Nanotechnol Res Ctr, Orumiyeh, Iran
[4] Univ Valencia, Dept Analyt Chem, Dr Moliner 50, E-46100 Burjassot, Spain
关键词
Peptide; Biosensing; Cancer; Tumor biomarkers; Nanoscience and nanotechnology; Biotechnology; Nucleic acid; Protein; Enzyme; Electrochemistry; SIGNAL-AMPLIFICATION ELEMENTS; TUMOR-SUPPRESSOR PROTEIN; TARGET-INDUCED CLEAVAGE; APTAMER-BASED BIOSENSOR; GRAPHENE QUANTUM DOTS; GOLD NANOPARTICLE; ELECTROCHEMICAL BIOSENSOR; CASPASE-3; ACTIVITY; NUCLEIC-ACID; FLUORESCENT BIOSENSOR;
D O I
10.1016/j.trac.2018.07.018
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This review provides an overview of the various types of (bio) sensors based on peptides for their analytical use, along with significant advances over the last several years in related technologies. So, it will be described: i) principles in biosensing using peptides ii) aspects of fabrication in the perspective of (bio) sensing applications iii) potential of electrochemical, electrochemiluminescence, photoelectrochemical, and optical (bio) sensors for the determination of target analytes within sub-nanomolar range also discussing the main problems in (bio) sensing iv) multiplex electrochemical and optical (bio) sensors, both with and without labels. v) Latest developments in the applications of (bio) sensors methods for detection of important analytes in real samples. vi) the application of nanotechnology and microfluidic technology on peptide based biosensing. (C) 2018 Elsevier B.V. All rights reserved.
引用
收藏
页码:1 / 20
页数:20
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