Hydroxymethylation and carbamoylation of di- and tetramethylpyridines using radical substitution (Minisci) reactions

被引：0
作者：
Biyouki, MAA
Smith, RAJ
Bedford, JJ
Leader, JP
机构：
[1] Univ Otago, Dept Chem, Dunedin, New Zealand
[2] Univ Otago, Sch Med Sci, Dept Physiol, Dunedin, New Zealand
来源：
SYNTHETIC COMMUNICATIONS | 1998年 / 28卷 / 20期
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D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reaction of hydroxymethyl radicals with N-methoxy 2,4- and 2,6-dimethylpyridinium salts gave 2,4,6-substituted hydroxymethylpyridines. Similar reactions with 2,3,5,6-tetramethylpyridine and derivatives failed, however 4-substitution could be achieved using a carbamoyl radical.
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页码：3817 / 3825
页数：9
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