New Tools to Test Stool Managing Travelers' Diarrhea in the Era of Molecular Diagnostics

被引：8

作者：

Eckbo, Eric J. ^{[1
]}

Yansouni, Cedric P. ^{[2
]}

Pernica, Jeffrey M. ^{[3
]}

Goldfarb, David M. ^{[4
,5
]}

机构：

[1] Univ British Columbia, Vancouver Gen Hosp, Dept Pathol & Lab Med, Div Med Microbiol, 899 West 12th Ave, Vancouver, BC V5Z 1M9, Canada

[2] McGill Univ, JD MacLean Ctr Trop Dis, Ctr Hlth, 1001 Blvd Decarie, Montreal, PQ H4A 3J1, Canada

[3] McMaster Univ, Dept Pediat, Div Infect Dis, Hamilton Hlth Sci Ctr, 1280 Main St West, Hamilton, ON L8S 4K1, Canada

[4] Univ British Columbia, Dept Pathol & Lab Med, Div Med Microbiol, Vancouver, BC, Canada

[5] Univ British Columbia, Dept Pediat, Div Infect Dis, Vancouver, BC, Canada

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2019年 / 33卷 / 01期

关键词：

Travelers' diarrhea; Enteric infections; Molecular testing; Multiplex PCR; Diagnostics; Shigella; Enterotoxigenic Escherichia coli; ANTIBIOTIC-RESISTANCE; INTERNATIONAL TRAVELERS; DEVELOPING-COUNTRIES; TROPHERYMA-WHIPPLEI; GIARDIA-LAMBLIA; RAPID DETECTION; UNITED-STATES; PCR ANALYSIS; DOUBLE-BLIND; CHILDREN;

D O I：

10.1016/j.idc.2018.10.012

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Travelers' diarrhea affects up to 60% of visitors to tropical and subtropical regions. Although symptoms are generally self-limited, some infections are associated with significant morbidity and occasional mortality. Newer molecular diagnostic techniques allow for highly sensitive, specific, and expeditious testing of a wide range of potential pathogens. Identification of the causative pathogen of travelers' diarrhea allows for targeted therapy and management and a reduction in empiric broad-spectrum coverage.

引用

页码：197 / +

页数：17

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