AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY POSITION STATEMENT ON THE ASSOCIATION OF SGLT-2 INHIBITORS AND DIABETIC KETOACIDOSIS

被引：269

作者：

Handelsman, Yehuda ^{[1
,2
]}

Henry, Robert R. ^{[3
,4
]}

Bloomgarden, Zachary T. ^{[5
]}

Dagogo-Jack, Sam ^{[6
]}

DeFronzo, Ralph A. ^{[7
]}

Einhorn, Daniel ^{[8
,9
,10
,11
,12
]}

Ferrannini, Ele ^{[13
]}

Fonseca, Vivian A. ^{[14
,15
,16
]}

Garber, Alan J. ^{[17
,18
,19
]}

Grunberger, George ^{[20
,21
,22
,23
,24
]}

LeRoith, Derek ^{[25
]}

Umpierrez, Guillermo E. ^{[26
,27
]}

Weir, Matthew R. ^{[28
,29
]}

机构：

[1] Metab Inst Amer, Tarzana, CA USA

[2] Amer Coll Endocrinol, Tarzana, CA USA

[3] Univ Calif San Diego, Med, San Diego, CA 92103 USA

[4] VA San Diego Healthcare Syst, Sect Diabet Endocrinol & Metab, San Diego, CA USA

[5] Icahn Sch Med Mt Sinai, New York, NY 10029 USA

[6] Univ Tennessee, Hlth Sci Ctr, Div Endocrinol Diabet & Metab, Memphis, TN USA

[7] Univ Texas Hlth Sci Ctr San Antonio, Diabet Div, San Antonio, TX 78229 USA

[8] Amer Coll Endocrinol, La Jolla, CA USA

[9] Amer Assoc Clin Endocrinologists, La Jolla, CA USA

[10] Scripps Whittier Diabet Inst, La Jolla, CA USA

[11] UCSD, Med, La Jolla, CA USA

[12] Diabet & Endocrine Associates, Journal Diabet, La Jolla, CA USA

[13] CNR, Inst Clin Physiol, Internal Med, Via Savi 8, I-56100 Pisa, Italy

[14] Tulane Univ, Hlth Sci Ctr, Med & Pharmacol, New Orleans, LA 70118 USA

[15] Tulane Univ, Hlth Sci Ctr, Diabet, New Orleans, LA 70118 USA

[16] Tulane Univ, Hlth Sci Ctr, Endocrinol Sect, New Orleans, LA 70118 USA

[17] Baylor Coll Med, Dept Med, Houston, TX 77030 USA

[18] Baylor Coll Med, Dept Biochem, Houston, TX 77030 USA

[19] Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA

[20] Amer Assoc Clin Endocrinologists, Bloomfield Hills, MI USA

[21] Grunberger Diabet Inst, Bloomfield Hills, MI USA

[22] Wayne State Univ, Sch Med, Internal Med & Mol Med & Genet, Detroit, MI USA

[23] Oakland Univ, William Beaumont Sch Med, Internal Med, Rochester, MI 48063 USA

[24] Charles Univ Prague, Fac Med 1, Internal Med, Prague, Czech Republic

[25] Mt Sinai Sch Med, Div Endocrinol Diabet & Bone Dis, Res, New York, NY USA

[26] Emory Univ, Sch Med, Med, Atlanta, GA USA

[27] Grady Hlth Syst, Endocrinol Sect, Atlanta, GA USA

[28] Univ Maryland, Sch Med, Div Nephrol, Baltimore, MD 21201 USA

[29] Univ Maryland, Sch Med, Med, Baltimore, MD 21201 USA

来源：

ENDOCRINE PRACTICE | 2016年 / 22卷 / 06期

关键词：

COTRANSPORTER; 2; INHIBITOR; ADJUNCT THERAPY; DOUBLE-BLIND; TYPE-1; INSULIN; GLUCOSE; SAFETY; DAPAGLIFLOZIN; LIPOLYSIS; EFFICACY;

D O I：

10.4158/EP161292.PS

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This document represents the official position of the American Association of Clinical Endocrinologists and American College of Endocrinology. Where there were no randomized controlled trials or specific U.S. FDA labeling for issues in clinical practice, the participating clinical experts utilized their judgment and experience. Every effort was made to achieve consensus among the committee members. Position and consensus statements are meant to provide guidance, but they are not to be considered prescriptive for any individual patient and cannot replace the judgment of a clinician.

引用

页码：753 / 762

页数：10

共 49 条

[1]

[Anonymous], 2015, INV CAN PRESCR INF

[2]

[Anonymous], 2015, JARD EMP PRESCR INF

[3]

[Anonymous], 2015, FARX DAP PRESCR INF

[4]

[Anonymous], 2015, FDA DRUG SAF COMM FD

[5] RENAL REABSORPTION AND UTILIZATION OF HYDROXYBUTYRATE AND ACETOACETATE IN STARVED RATS [J].

BARACNIETO, M .

AMERICAN JOURNAL OF PHYSIOLOGY, 1986, 251 (02) :F257-F265

[6]

Benstetter M., 2016, SGLT2 INHIBITORS PRA

[7] RELATIONSHIP BETWEEN SEVERITY OF HYPERGLYCEMIA AND METABOLIC-ACIDOSIS IN DIABETIC-KETOACIDOSIS [J].

BRANDT, KR ;

MILES, JM .

MAYO CLINIC PROCEEDINGS, 1988, 63 (11) :1071-1074

[8] Efficacy and safety of low-carbohydrate diets - A systematic review [J].

Bravata, DM ;

Sanders, L ;

Huang, J ;

Krumholz, HM ;

Olkin, I ;

Gardner, CD ;

Bravata, DM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 289 (14) :1837-1850

[9] Differential effects of fasting and dehydration in the pathogenesis of diabetic ketoacidosis [J].

Burge, MR ;

Garcia, N ;

Qualls, CR ;

Schade, DS .

METABOLISM-CLINICAL AND EXPERIMENTAL, 2001, 50 (02) :171-177

[10] Fuel metabolism in starvation [J].

Cahill, George F., Jr. .

ANNUAL REVIEW OF NUTRITION, 2006, 26 :1-22

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