Intravenous immunoglobulin (IVIg) is often used as preferred treatment in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Several studies highlighted the short-term efficacy of IVIg for CIDP yet many patients need maintenance therapy. Notwithstanding the fact IVIg has been used for over 30 years in CIDP, there is only limited evidence to guide dosage and interval during maintenance treatment. The variation in disease course, lack of biomarkers, and fear of deterioration after stopping IVIg makes long-term treatment challenging. Recent studies suggest a proportion of patients receive unnecessary IVIg maintenance treatment. This review provides an overview of the use of IVIg for CIDP treatment, focusing on evidence for long-term IVIg use.
机构:Chaim Sheba Med Ctr, Dept Med B, Ctr Autoimmune Dis, IL-52621 Tel Hashomer, Israel
Orbach, H
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Katz, U
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机构:Chaim Sheba Med Ctr, Dept Med B, Ctr Autoimmune Dis, IL-52621 Tel Hashomer, Israel
Katz, U
;
Sherer, V
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机构:Chaim Sheba Med Ctr, Dept Med B, Ctr Autoimmune Dis, IL-52621 Tel Hashomer, Israel
Sherer, V
;
Shoenfeld, Y
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机构:
Chaim Sheba Med Ctr, Dept Med B, Ctr Autoimmune Dis, IL-52621 Tel Hashomer, IsraelChaim Sheba Med Ctr, Dept Med B, Ctr Autoimmune Dis, IL-52621 Tel Hashomer, Israel
机构:Chaim Sheba Med Ctr, Dept Med B, Ctr Autoimmune Dis, IL-52621 Tel Hashomer, Israel
Orbach, H
;
Katz, U
论文数: 0引用数: 0
h-index: 0
机构:Chaim Sheba Med Ctr, Dept Med B, Ctr Autoimmune Dis, IL-52621 Tel Hashomer, Israel
Katz, U
;
Sherer, V
论文数: 0引用数: 0
h-index: 0
机构:Chaim Sheba Med Ctr, Dept Med B, Ctr Autoimmune Dis, IL-52621 Tel Hashomer, Israel
Sherer, V
;
Shoenfeld, Y
论文数: 0引用数: 0
h-index: 0
机构:
Chaim Sheba Med Ctr, Dept Med B, Ctr Autoimmune Dis, IL-52621 Tel Hashomer, IsraelChaim Sheba Med Ctr, Dept Med B, Ctr Autoimmune Dis, IL-52621 Tel Hashomer, Israel